28 Jul 2022

Review reinforces link between contraceptive pill and depression

Progestin based hormonal contraceptive pills can tip vulnerable
women into depression, review shows

by Anne Crawford

For some time, Monash Central Clinical School psychiatrist Professor Jayashri Kulkarni has treated women telling her they had developed depression since being prescribed certain oral contraception or that their existing depression had become out of control.

Platelets and their response to acute changes in blood flow

L-R: Ms Nurul Abidin Zainal, Dr Warwick Nesbitt and Dr Crispin Szydzik
are authors on the paper
In world-first research to combine computational models of blood flow with single platelet signalling studies, a Monash collaborative study has found that platelets are able to sense acute changes in blood flow found within diseased vessels or blood-contacting devices through a unique mechano-sensor. 

The team includes Australian Centre for Blood Diseases (ACBD) researchers, in collaboration with Alfred Health, University of Melbourne (Engineering & Medicine) and RMIT University (Engineering).

27 Jul 2022

19-25 July 2022 Central Clinical School recent publications

A systematic review of perioperative clinical trials in Australia found there
was very little consumer engagement in formulation, management, conduct
and dissemination of the trial findings.
Recent publications featuring research as notified by PubMed during 19-25 July 2022 from Central Clinical School affiliated researchers in the following departments.

The most recent validated publications for the school and departments can be seen on their publications pages, linked to from the headings below. Otherwise, read down the entry for recent notifications. The below is not a comprehensive list.

Sexual health researchers nominated for Eureka Prize

L-R: Prof Kit Fairley, A/Prof Eric Chow, Prof Marcus Chen, Prof
Jane Hocking,
Prof Deborah Williamson, Prof Catriona Bradshaw
Four Medicine, Nursing and Health Sciences research projects across the ‘Research and Innovation’ and ‘Leadership’ categories have been named as finalists in the 2022 Australian Museum Eureka Prize, including members of Central Clinical School's Melbourne Sexual Health Centre (MSHC).

The Eureka Prizes honour excellence across the areas of research and innovation, leadership, science engagement and school science, and are presented annually in partnership with some of the country’s leading scientific institutions, government organisations, universities and corporations.

See all four Monash MNHS finalists shortlisted for the 2022 Australian Museum Eureka Prizes in the faculty story and MSHC detail below. 

Join the De Castella run 28 July 2022 to support mental health

The de Castella Run, which the Monash Alfred Psychiatry research centre helped organise in previous years, is raising funds for One in Five. One in Five are supporting the newly established HER Centre Australia. If you can support this event by volunteering, running or walking for mental health at the event on 28 August, go to the website and sign up as a participant.

23 Jul 2022

New discovery could pave the way for improved treatments for diabetes

L-R: Dr Keith Al-Hasani, Dr Ishant Khurana and Professor Sam
El-Osta, lead authors on the beta cell regeneration study. Ishant
 Khurana explains more about the research
in a video (1:02 mins)
 and see animation

In a world-first, a study by Monash University has discovered a pathway to the regeneration of insulin in pancreatic stem cells, a major breakthrough toward new therapies to treat Type 1 and Type 2 diabetes.  

Using the pancreas stem cells of type 1 diabetic donor, researchers were able to effectively reactivate them to become insulin-expressing and functionally resemble beta-like cells through the use of a drug which is approved by the US Food and Drug Administration but is not currently licensed for diabetes treatment.  

The new approach, though it requires further work, would in principle allow insulin-producing cells (beta-cells) that are destroyed in type 1 diabetics to be replaced with newborn insulin-generating cells.

22 Jul 2022

Dr Emily Edwards wins ASPIRE award for primary immunodeficiency research

Dr Emily Edwards has received an ASPIRE award

Congratulations to Dr Emily Edwards for winning the ASPIRE award presented by Grifols. The ASPIRE  (Award for Scientific Progress in Immunodeficiency Research) Award program is particularly interested in innovative ideas in the field of primary and secondary immunodeficiencies and the role of immunoglobulin therapy.

As part of this prestigious international award, Emily will receive €50,000 for her project, "Advancing the Genetic Diagnosis of Predominantly Antibody Deficiency through Development and Implementation of Functional Diagnostic Screening Assays." 

The project will support Emily's ongoing work in collaboration with Dr Julian Bosco and Prof Robyn O'Hehir (Alfred Health), Dr Samar Ojaimi (Monash Health), Dr Jason Fok (Eastern Health) and A/Prof Menno van Zelm (Monash University), and will be awarded at the ESID conference in Gothenburg, Sweden in October.

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