Symptoms of depression during perimenopause were found to present as subtly different to that seen during the childbearing years, with increased anger, reduced sleep quality, and increased fatigue that was independent of sleep quality. The researchers conclude that there is unique presentation of perimenopausal depression which identifies targets for intervention and different treatment options.
Reference: Gibbs Z, Lee S and Kulkarni J. The unique symptom profile of perimenopausal depression. Clinical Psychologist, 19(2), pp.76–84, July 2015