2 Feb 2018

Recent CCS publications: 15 Dec 2017 - 1 Jan 2018

Prof Leon Bach, Department of Medicine
(Alfred) published a paper on insulin-like
growth factor binding proteins, implicated
in disorders including malignant, metabolic,
neurological and immune diseases
Recent publications for Central Clinical School affiliated authors in the following departments. Note, browse down this entry for complete publications list. Linked headings for each section are to the departments' home pages.

  • Allergy, Immunology and Respiratory Medicine (AIRMed)
  • Anaesthesia and Perioperative Medicine
  • Australian Centre for Blood Diseases (ACBD)
  • Centre for Obesity Research and Education (CORE)
  • Diabetes
  • Gastroenterology
  • Infectious Diseases
  • Immunology
  • MAPrc
  • Medicine
  • Melbourne Sexual Health Clinic (MSHC)
  • Neuroscience
  • Surgery


    French SL, Hamilton JR. Drugs targeting protease-activated receptor-4 improve the anti-thrombotic therapeutic window. Ann Transl Med. 2017 Dec;5(23):464. doi: 10.21037/atm.2017.09.10.

    Keragala CB, Draxler DF, McQuilten ZK, Medcalf RL. Haemostasis and innate immunity - a complementary relationship: A review of the intricate relationship between coagulation and complement pathways. Br J Haematol. 2017 Dec 19. doi: 10.1111/bjh.15062. [Epub ahead of print]

    Ong DM, Farrugia H, Wei A. Therapy-Related Acute Myeloid Leukaemia and Myelodysplastic Syndrome in Victoria, Australia 2003-2014. Intern Med J. 2017 Dec 13. doi: 10.1111/imj.13714. [Epub ahead of print]

    Stryjewska A et al, Haigh JJ. Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells. Stem Cells. 2017 Mar;35(3):611-625. doi: 10.1002/stem.2521. Epub 2016 Nov 8.

    Wei AH, Tiong IS. Midostaurin, enasidenib, CPX-351, gemtuzumab ozogamicin, and venetoclax bring new hope to AML. Blood. 2017 Dec 7;130(23):2469-2474. doi: 10.1182/blood-2017-08-784066. Epub 2017 Oct 19.


    Lee J, Kronborg C, O'Hehir RE, Hew M. Who's at risk of thunderstorm asthma? The ryegrass pollen trifecta and lessons learnt from the Melbourne thunderstorm epidemic. Respir Med. 2017 Nov;132:146-148. doi: 10.1016/j.rmed.2017.10.012. Epub 2017 Oct 18.

    Nugraha R, Kamath SD, Johnston E, Zenger KR, Rolland JM, O'Hehir RE, Lopata AL. Rapid and comprehensive discovery of unreported shellfish allergens using large-scale transcriptomic and proteomic resources. J Allergy Clin Immunol. 2017 Dec 16. pii: S0091-6749(17)32915-9. doi: 10.1016/j.jaci.2017.11.028. [Epub ahead of print]

    Sands SA et al. Quantifying the Arousal Threshold using Polysomnography in Obstructive Sleep Apnea. Sleep. 2017 Nov 9. doi: 10.1093/sleep/zsx183. [Epub ahead of print]


    Dieleman JM, Peelen LM, Coulson TG, Tran L, Reid CM, Smith JA, Myles PS, Pilcher D. Age and other perioperative risk factors for postoperative systemic inflammatory response syndrome after cardiac surgery. Br J Anaesth. 2017 Oct 1;119(4):637-644. doi: 10.1093/bja/aex239.


    Long AJ, Burton PR, De Veer MJ, Ooi GJ, Laurie CP, Nottle PD, Watt MJ, Brown WA. Radical gastric cancer surgery results in widespread upregulation of pro-tumourigenic intraperitoneal cytokines. ANZ J Surg. 2017 Nov 30. doi: 10.1111/ans.14267. [Epub ahead of print]

    Motyer R1 et al, O'Brien P. Outcomes of endovascular treatment for acute large-vessel ischaemic stroke more than 6 h after symptom onset. J Intern Med. 2017 Dec;282(6):537-545. doi: 10.1111/joim.12680. Epub 2017 Sep 25.

    Wentworth JM et al. O'Brien PE. Interferon-gamma released from omental adipose tissue of insulin-resistant humans alters adipocyte phenotype and impairs response to insulin and adiponectin release. Int J Obes (Lond). 2017 Dec;41(12):1782-1789. doi: 10.1038/ijo.2017.180. Epub 2017 Aug 3.

    Alrashdi SF, Deliyanti D, Talia DM, Wilkinson-Berka JL. Endothelin-2 Injures the Blood-Retinal Barrier and Macroglial Müller Cells: Interactions with Angiotensin II, Aldosterone, and NADPH Oxidase.Am J Pathol. 2017 Dec 15. pii: S0002-9440(17)30739-3. doi: 10.1016/j.ajpath.2017.11.009. [Epub ahead of print]

    Ung L, Pattamatta U, Carnt N, Wilkinson-Berka JL, Liew G, White AJR. Oxidative stress and reactive oxygen species: a review of their role in ocular disease. Clin Sci (Lond). 2017 Dec 4;131(24):2865-2883. doi: 10.1042/CS20171246. Print 2017 Dec 15.


    Choy MC et al. Sparrow MP. Predicting Response after Infliximab Salvage in Acute Severe Ulcerative Colitis. J Gastroenterol Hepatol. 2017 Dec 21. doi: 10.1111/jgh.14072. [Epub ahead of print]

    Christensen B, Sparrow MP. Editorial: international consensus in clinical trial end-points in ulcerative colitis - clarity or just a step in clearing the fog? Aliment Pharmacol Ther. 2017 May;45(9):1274-1275. doi: 10.1111/apt.14007.

    Costa RJS, Snipe RMJ, Kitic CM, Gibson PR. Systematic review: exercise-induced gastrointestinal syndrome-implications for health and intestinal disease. Aliment Pharmacol Ther. 2017 Aug;46(3):246-265. doi: 10.1111/apt.14157. Epub 2017 Jun 7.

    Dwyer JP, Tan JYC, Urquhart P, Secomb R, Bunn C, Reynolds J, La Nauze R, Kemp W, Roberts S, Brown G. A prospective comparison of cold snare polypectomy using traditional or dedicated cold snares for the resection of small sessile colorectal polyps. Endosc Int Open. 2017 Nov;5(11):E1062-E1068. doi: 10.1055/s-0043-113564. Epub 2017 Oct 27.

    Gibson PR, Halmos EP, Muir JG. Letter: bias in clinical trials of the symptomatic effects of the low FODMAP diet for irritable bowel syndrome-getting the facts right. Aliment Pharmacol Ther. 2017 Aug;46(3):385-386. doi: 10.1111/apt.14150.

    McCaughan GW et al. Roberts SK; Australian Liver Association Clinical Research Network. Sofosbuvir and daclatasvir therapy in patients with hepatitis C-related advanced decompensated liver disease (MELD ≥ 15). Aliment Pharmacol Ther. 2018 Feb;47(3):401-411. doi: 10.1111/apt.14404. Epub 2017 Dec 5.

    Roberts SK, Kemp W. Salvage Therapies for Autoimmune Hepatitis: A Critical Review. Semin Liver Dis. 2017 Nov;37(4):343-362. doi: 10.1055/s-0037-1607453. Epub 2017 Dec 22.

    Snipe RMJ, Khoo A, Kitic CM, Gibson PR, Costa RJS. The impact of exertional-heat stress on gastrointestinal integrity, gastrointestinal symptoms, systemic endotoxin and cytokine profile. Eur J Appl Physiol. 2018 Feb;118(2):389-400. doi: 10.1007/s00421-017-3781-z. Epub 2017 Dec 12.

    Ward MG, Gibson PR, Sparrow MP. Editorial: variability in adalimumab trough and peak serum concentrations - authors' reply.Aliment Pharmacol Ther. 2017 Jun;45(11):1476-1477. doi: 10.1111/apt.14091.

    Younossi ZM, Stepanova M, Sulkowski M, Foster GR, Reau N, Mangia A, Patel K, Bräu N, Roberts SK, Afdhal N, Nader F, Henry L, Hunt S. Ribavirin-Free Regimen With Sofosbuvir and Velpatasvir Is Associated With High Efficacy and Improvement of Patient-Reported Outcomes in Patients With Genotypes 2 and 3 Chronic Hepatitis C: Results From Astral-2 and -3 Clinical Trials. Clin Infect Dis. 2016 Oct 15;63(8):1042-1048. doi: 10.1093/cid/ciw496. Epub 2016 Jul 20.


    Jansen MAE, van den Heuvel D, Jaddoe VWV, van Zelm MC, Moll HA. Abnormalities in CD57+ cytotoxic T cells and Vδ1+ γδT cells in subclinical celiac disease in childhood are affected by cytomegalovirus. The Generation R Study. Clin Immunol. 2017 Oct;183:233-239. doi: 10.1016/j.clim.2017.04.008. Epub 2017 Apr 26.

    Noho-Konteh F et al, Plebanski M, Flanagan KL. Sex-Differential Non-Vaccine-Specific Immunological Effects of Diphtheria-Tetanus-Pertussis and Measles Vaccination.Clin Infect Dis. 2016 Nov 1;63(9):1213-1226. Epub 2016 Jul 19.

    Tran J, Wilson K, Plebanski M, Flanagan KL. Manipulating the microbiota to improve human health throughout life. Trans R Soc Trop Med Hyg. 2017 Dec 13. doi: 10.1093/trstmh/trx068. [Epub ahead of print]

    Infectious Diseases

    Abbott IJ, Meletiadis J, Belghanch I, Wijma RA, Kanioura L, Roberts JA, Peleg AY, Mouton JW. Fosfomycin efficacy and emergence of resistance among Enterobacteriaceae in an in vitro dynamic bladder infection model. J Antimicrob Chemother. 2017 Dec 14. doi: 10.1093/jac/dkx441. [Epub ahead of print]

    Christoff RM, Murray GL, Kostoulias XP, Peleg AY, Abbott BM. Synthesis of novel 1,2,5-oxadiazoles and evaluation of action against Acinetobacter baumannii. Bioorg Med Chem. 2017 Dec 15;25(24):6267-6272. doi: 10.1016/j.bmc.2017.08.015. Epub 2017 Aug 10.

    Wong SW et al, Cheng AC. The influence of intensive care unit-acquired central line-associated bloodstream infection on in-hospital mortality: A single-center risk-adjusted analysis. Am J Infect Control. 2016 May 1;44(5):587-92. doi: 10.1016/j.ajic.2015.12.008. Epub 2016 Feb 10.

    Yong YK, Shankar EM, Solomon A, Spelman T, Fairley CK, Elliott JH, Hoy J, Cameron PU, Kamarulzaman A, Lewin SR. Polymorphisms in the CD14 and TLR4 genes independently predict CD4+ T-cell recovery in HIV-infected individuals on antiretroviral therapy. AIDS. 2016 Sep 10;30(14):2159-68. doi: 10.1097/QAD.0000000000001179.


    Che X, Cash R, Fitzgerald P, Fitzgibbon BM. The Social Regulation of Pain: Autonomic and Neurophysiological Changes Associated with Perceived Threat. J Pain. 2017 Dec 20. pii: S1526-5900(17)30816-7. doi: 10.1016/j.jpain.2017.12.007. [Epub ahead of print]

    Fitzgerald PB, Hoy KE, Anderson RJ, Daskalakis ZJ. A STUDY OF THE PATTERN OF RESPONSE TO rTMS TREATMENT IN DEPRESSION. Depress Anxiety. 2016 Aug;33(8):746-53. doi: 10.1002/da.22503. Epub 2016 Apr 5.

    Jablensky A et al. Kulkarni J. The 2016 RANZCP Guidelines for the Management of Schizophrenia and Related Disorders - what's next? Australas Psychiatry. 2017 Dec;25(6):600-602. doi: 10.1177/1039856217726691. Epub 2017 Sep 6.

    Manning V et al, Kulkarni J. Problem gambling and substance use in patients attending community mental health services. J Behav Addict. 2017 Dec 1;6(4):678-688. doi: 10.1556/2006.6.2017.077. Epub 2017 Dec 19.

    Phillipou A, Rossell SL, Gurvich C, Castle DJ, Abel LA, Nibbs RG, Hughes ME. Differences in regional grey matter volumes in currently ill patients with anorexia nervosa. Eur J Neurosci. 2018 Jan;47(2):177-183. doi: 10.1111/ejn.13793. Epub 2018 Jan 10.


    Bach LA. IGF binding proteins. J Mol Endocrinol. 2017 Dec 18. pii: JME-17-0254. doi: 10.1530/JME-17-0254. [Epub ahead of print]

    Charidimou et al. Srikanth V.; International META-MICROBLEEDS Initiative. Brain microbleeds, anticoagulation, and hemorrhage risk: Meta-analysis in stroke patients with AF. Neurology. 2017 Dec 5;89(23):2317-2326. doi: 10.1212/WNL.0000000000004704. Epub 2017 Nov 8.

    Darido C, Georgy SR, Cullinane C, Partridge DD, Walker R, Srivastava S, Roslan S, Carpinelli MR, Dworkin S, Pearson RB, Jane SM. Stage-dependent therapeutic efficacy in PI3K/mTOR-driven squamous cell carcinoma of the skin. Cell Death Differ. 2017 Dec 13. doi: 10.1038/s41418-017-0032-0. [Epub ahead of print]

    Miles LB, Darido C, Kaslin J, Heath JK, Jane SM, Dworkin S. Mis-expression of grainyhead-like transcription factors in zebrafish leads to defects in enveloping layer (EVL) integrity, cellular morphogenesis and axial extension. Sci Rep. 2017 Dec 14;7(1):17607. doi: 10.1038/s41598-017-17898-7.

    Riddell MA et al. Srikanth V.  Developing consensus measures for global programs: lessons from the Global Alliance for Chronic Diseases Hypertension research program. Global Health. 2017 Mar 15;13(1):17. doi: 10.1186/s12992-017-0242-8.

    Somri L, Sarfstein R, Lapkina-Gendler L, Nagaraj K, Laron Z, Bach LA, Werner H. Differential expression of IGFBPs in Laron syndrome-derived lymphoblastoid cell lines: Potential correlation with reduced cancer incidence. Growth Horm IGF Res. 2017 Nov 24. pii: S1096-6374(17)30106-5. doi: 10.1016/j.ghir.2017.11.004. [Epub ahead of print]

    Veloudi P, Blizzard CL, Srikanth VK, Schultz MG, Sharman JE. Influence of blood pressure level and age on within-visit blood pressure variability in children and adolescents. Eur J Pediatr. 2018 Feb;177(2):205-210. doi: 10.1007/s00431-017-3049-y. Epub 2017 Dec 4.


    Audsley J. et al, Fairley CK. Effects of long-term tenofovir-based combination antiretroviral therapy in HIV-hepatitis B virus coinfection on persistent hepatitis B virus viremia and the role of hepatitis B virus quasispecies diversity. AIDS. 2016 Jun 19;30(10):1597-606. doi: 10.1097/QAD.0000000000001080.

    Boettiger DC1 et al, O'Connor CC, Fairley CK. Hepatitis C testing and re-testing among people attending sexual health services in Australia, and hepatitis C incidence among people with human immunodeficiency virus: analysis of national sentinel surveillance data. BMC Infect Dis. 2017 Dec 1;17(1):740. doi: 10.1186/s12879-017-2848-0.

    Cornelisse VJ, Priest D, Fairley CK, Walker S, Bradshaw CS, Phillips T, Chow EP. The frequency of kissing as part of sexual activity differs depending on how men meet their male casual sexual partners. Int J STD AIDS. 2017 Jan 1:956462417748717. doi: 10.1177/0956462417748717. [Epub ahead of print

    Drolet M, Laprise J, Brotherton JML, Donovan B, Fairley CK, Ali H, Bénard É, Martin D, Brisson M. The Impact of Human Papillomavirus Catch-Up Vaccination in Australia: Implications for Introduction of Multiple Age Cohort Vaccination and Postvaccination Data Interpretation. J Infect Dis. 2017 Dec 5;216(10):1205-1209. doi: 10.1093/infdis/jix476.

    Fairley CK, Chow EPF. Doxycycline post-exposure prophylaxis: let the debate begin. Lancet Infect Dis. 2017 Dec 8. pii: S1473-3099(17)30726-0. doi: 10.1016/S1473-3099(17)30726-0. [Epub ahead of print]

    Jamil MS et al. Chen M, Medland N, Fairley CK; ACCESS and NSW Partnership Project Steering Committees. Understanding the Targeting and Uptake of HIV Testing Among Gay and Bisexual Men Attending Sexual Health Clinics. AIDS Behav. 2017 Dec 19. doi: 10.1007/s10461-017-2012-2. [Epub ahead of print]

    Leeyaphan C, Ong JJ, Chow EP, Dimovski K, Kong FY, Hocking JS, Howden B, Bissessor M, Fairley CK, Bradshaw C, Read T, Chen M. Treatment Outcomes for Rectal Lymphogranuloma Venereum in Men Who Have Sex with Men Using Doxycycline, Azithromycin, or Both: A Review of Clinical Cases.Sex Transm Dis. 2017 Apr;44(4):245-248. doi: 10.1097/OLQ.0000000000000578.

    Ong JJ et al. Fairley CK. Opportunities and barriers to STI testing in community health centres in China: a nationwide survey. Sex Transm Infect. 2017 Dec;93(8):566-571. doi: 10.1136/sextrans-2017-053196. Epub 2017 Aug 26.

    Rane V, Tomnay J, Fairley C, Read T, Bradshaw C, Carter T, Chen M. Opt-Out Referral of Men Who Have Sex With Men Newly Diagnosed With HIV to Partner Notification Officers: Results and Yield of Sexual Partners Being Contacted. Sex Transm Dis. 2016 Jun;43(6):341-5. doi: 10.1097/OLQ.0000000000000449.

    Tan WS, Chow EP, Fairley CK, Chen MY, Bradshaw CS, Read TR. Sensitivity of HIV rapid tests compared with fourth-generation enzyme immunoassays or HIV RNA tests. AIDS. 2016 Jul 31;30(12):1951-60. doi: 10.1097/QAD.0000000000001134.


    Clough M et al. O'Brien TJ. Oculomotor cognitive control abnormalities in Australian rules football players with a history of concussion. J Neurotrauma. 2017 Dec 11. doi: 10.1089/neu.2017.5204. [Epub ahead of print]

    Kiral-Kornek I et al. O'Brien T. Epileptic Seizure Prediction Using Big Data and Deep Learning: Toward a Mobile System. EBioMedicine. 2017 Dec 12. pii: S2352-3964(17)30470-X. doi: 10.1016/j.ebiom.2017.11.032. [Epub ahead of print]

    Semple BD, Dixit S, Shultz SR, Boon WC, O'Brien TJ. Sex-dependent changes in neuronal morphology and psychosocial behaviors after pediatric brain injury. Behav Brain Res. 2017 Feb 15;319:48-62. doi: 10.1016/j.bbr.2016.10.045. Epub 2016 Nov 6.


    Brichko L, Giddey B, Tee J, Niggemeyer L, Fitzgerald M. Cervical spine traumatic epidural haematomas: Incidence and characteristics. Emerg Med Australas. 2017 Dec 21. doi: 10.1111/1742-6723.12920. [Epub ahead of print]

    Cleland H. The Burns Registry of Australia and New Zealand: progressing the evidence base for burn care. Med J Aust. 2016 Aug 15;205(4):191.

    Ekegren CL et al. Liew S. Twelve-month work-related outcomes following hip fracture in patients under 65 years of age. Injury. 2017 Mar;48(3):701-707. doi: 10.1016/j.injury.2017.01.033. Epub 2017 Jan 18.

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