CCS recent publications 3-10 October 2018

Scan of lungs with fungal lesions obtained using NLP. These data are
now being used to train a deep learning image classifier to better help

clinicians pick up fungal infections. Green circles are fungal lesions 

labeled by the radiologists. Orange are NLP identified.
See this week's feature

Recent publications from Central Clinical School affiliated researchers in the following departments:

• AIRmed
• Diabetes
• Gastroenterology
• Immunology and Pathology
• Infectious Diseases
• Medicine
• Melbourne Sexual Health Centre
• Monash Alfred Psychiatry research cntr
• Neuroscience
• Peninsula Clinical School
• Surgery

Department of Allergy, Immunology and Respiratory Medicine

Bousquet JJ, Schünemann HJ, Togias A, ... O'Hehir R, ...Zhang L, Zhong NS, Zidarn M; ARIA Study Group; MASK Study Group. Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases. Clin Transl Allergy. 2019 Sep 9;9:44. doi: 10.1186/s13601-019-0279-2. eCollection 2019.

Sant S, Jenkins MR, Dash P, Watson KA , Wang Z, Pizzolla A, Koutsakos M, Nguyen TH, Lappas M, Crowe J, Loudovaris T, Mannering SI, Westall GP, Kotsimbos TC, Cheng AC, Wakim L, Doherty PC, Thomas PG, Loh L, Kedzierska K. Human yd T-cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation. Clin Transl Immunology. 2019 Sep 23;8(9):e1079. doi: 10.1002/cti2.1079. eCollection 2019.


Department of Diabetes

Findeisen M, Allen TL, Henstridge DC, ... Febbraio MA. Treatment of type 2 diabetes with the designer cytokine IC7Fc. Nature. 2019 Sep 25. doi: 10.1038/s41586-019-1601-9. [Epub ahead of print]

Cheng E, Longmore D, Barzi F, Barr ELM, Lee I, Whitbread C, Boyle JA, Oats J, Connors C, McIntyre HD, Kirkwood M, Dempsey K, Zhang X, Thomas S, Williams D, Zimmet P, Brown ADH, Shaw JE, Maple-Brown L; PANDORA Study research team. Birth outcomes in women with gestational diabetes managed by lifestyle modification alone: The PANDORA Study. Diabetes Res Clin Pract. 2019 Oct 3:107876. doi: 10.1016/j.diabres.2019.107876.

Tan SM, Ziemann M, Thallas-Bonke V, Snelson M, Kumar V, Laskowski A, Nguyen TV, Huynh K, Clarke MV, Libianto R, Baker ST, Skene A, Power DA, MacIsaac RJ, Henstridge DC, Wetsel RA, El-Osta A, Meikle PJ, Wilson SG, Forbes JM, Cooper ME, Ekinci EI, Woodruff TM, Coughlan MT. Complement C5a Induces Renal Injury in Diabetic Kidney Disease Via Disruption in Mitochondrial Metabolic Agility. Diabetes. 2019 Oct 17. pii: db190043. doi: 10.2337/db19-0043.


Department of Gastroenterology

Tuck CJ, Reed DE, Muir J, Vanner SJ. Implementation of the low FODMAP diet in functional gastrointestinal symptoms: A real-world experience. Neurogastroenterol Motil. 2019 Sep 30:e13730. doi: 10.1111/nmo.13730. [Epub ahead of print]


Department of Immunology and Pathology

van Zelm MC, McKenzie CI, Varese N, Rolland JM, O'Hehir RE. Recent Developments and Highlights in Immune Monitoring of Allergen Immunotherapy. Allergy. 2019 Oct 6. doi: 10.1111/all.14078. [Epub ahead of print]


Department of Infectious Diseases

Baggio D, Peel T, Peleg AY, Avery S, Prayaga M, Foo M, Haffari G, Liu M, Bergmeir C, Ananda-Rajah M. Closing the Gap in Surveillance and Audit of Invasive Mold Diseases for Antifungal Stewardship Using Machine Learning. J Clin Med. 2019 Sep 5;8(9). pii: E1390. doi: 10.3390/jcm8091390.

Cheng AC, Holmes M, Dwyer DE, Senanayake S, Cooley L, Irving LB, Simpson G, Korman T, Macartney K, Friedman ND, Wark P, Howell A, Blyth CC, Bowler S, Upham J, Waterer GW, Kotsimbos T, Kelly PM. Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2017: the Influenza Complications Alert Network (FluCAN). Commun Dis Intell (2018). 2019 Sep 16;43. doi: 10.33321/cdi.2019.43.39.

Gardiner BJ, Chow JK, Brilleman SL, Peleg AY , Snydman DR. The impact of recurrent cytomegalovirus infection on long-term survival in solid organ transplant recipients. Transpl Infect Dis. 2019 Oct 3:e13189. doi: 10.1111/tid.13189.

Guérillot R, Kostoulias X, Donovan L1, ... Peleg AY, Stinear TP, Howden BP. Unstable chromosome rearrangements in Staphylococcus aureus cause phenotype switching associated with persistent infections. Proc Natl Acad Sci U S A. 2019 Sep 16. pii: 201904861. doi: 10.1073/pnas.1904861116.

Luu S, Spelman D, Woolley IJ. Post-splenectomy sepsis: preventative strategies, challenges, and solutions. Infect Drug Resist. 2019 Sep 12;12:2839-2851. doi: 10.2147/IDR.S179902. eCollection 2019.

Patton T, Jiang JH, Lundie RJ, Bafit M, Gao W, Peleg AY, O'Keeffe M. Daptomycin resistant Staphylococcus aureus clinical isolates are poorly sensed by dendritic cells. Immunol Cell Biol. 2019 Sep 26. doi: 10.1111/imcb.12295. [Epub ahead of print]


Department of Medicine

Darido C, Georgy SR, Cullinane C, Partridge DD4, Walker R, Srivastava S, Roslan S, Carpinelli MR, Dworkin S, Pearson RB, Jane SM. Stage-dependent therapeutic efficacy in PI3K/mTOR-driven squamous cell carcinoma of the skin. Cell Death Differ. 2018 Jun;25(6):1146-1159. doi: 10.1038/s41418-017-0032-0. Epub 2017 Dec 13.


Melbourne Sexual Health Centre

Chow EPF, Tabrizi SN, Fairley CK, Wigan R, Machalek DA, Regan DG, Hocking JS, Garland SM, Cornall AM, Atchison S, Bradshaw CS, McNulty A, Owen L, Marshall L, Russell DB, Kaldor JM, Chen MY. Prevalence of human papillomavirus in teenage heterosexual males following the implementation of female and male school-based vaccination in Australia: 2014-2017. Vaccine. 2019 Sep 24. pii: S0264-410X(19)31261-7. doi: 10.1016/j.vaccine.2019.09.052. [Epub ahead of print] PMID: 31562001 [PubMed - as supplied by publisher]

Plummer EL, Vodstrcil LA, Murray GL, Fairley CK, Danielewski JA, Garland SM, Chow EPF, Bulach DM, Fethers KA, Hocking JS, Bradshaw CS. Gardnerella vaginalis clade distribution is associated with behavioural practices and Nugent Score in women who have sex with women. J Infect Dis. 2019 Sep 23. pii: jiz474. doi: 10.1093/infdis/jiz474. [Epub ahead of print] PMID: 31544206 [PubMed - as supplied by publisher]

Chi Wai Wong W, Tsz Hei Lau S, Pui Hang Choi E, Tucker JD, Fairley CK, Saunders JM. A Systematic Literature Review of Reviews on the Effectiveness of Chlamydia Screening. Epidemiol Rev. 2019 Sep 30. pii: mxz007. doi: 10.1093/epirev/mxz007. [Epub ahead of print]


Monash Alfred Psychiatry research centre

Ahmadizadeh MJ, Rezaei M, Fitzgerald PB. Transcranial direct current stimulation (tDCS) for post-traumatic stress disorder (PTSD): A randomized, double-blinded, controlled trial. Brain Res Bull. 2019 Sep 24. pii: S0361-9230(19)30655-0. doi: 10.1016/j.brainresbull.2019.09.011. [Epub ahead of print]

Pirotta S, Barillaro M, Brennan L, Grassi A , Jeanes YM, Joham AE, Kulkarni J, Couch LM, Lim SS, Moran LJ. Disordered Eating Behaviours and Eating Disorders in Women in Australia with and without Polycystic Ovary Syndrome: A Cross-Sectional Study. J Clin Med. 2019 Oct 14;8(10). pii: E1682. doi: 10.3390/jcm8101682.

Thomas N, Gurvich C, Kulkarni J. Borderline personality disorder, trauma, and the hypothalamus-pituitary-adrenal axis. Neuropsychiatr Dis Treat. 2019 Sep 9;15:2601-2612. doi: 10.2147/NDT.S198804. eCollection 2019.


Department of Neuroscience

Cardoso BR, Roberts BR, Malpas CB, Vivash L, Genc S, Saling MM, Desmond P, Steward C, Hicks RJ, Callahan J, Brodtmann A, Collins S, Macfarlane S, Corcoran NM, Hovens CM, Velakoulis D, O'Brien TJ, Hare DJ, Bush AI. Supranutritional Sodium Selenate Supplementation Delivers Selenium to the Central Nervous System: Results from a Randomized Controlled Pilot Trial in Alzheimer's Disease. Neurotherapeutics. 2019 Jan;16(1):192-202. doi: 10.1007/s13311-018-0662-z. PMID: 30215171

Janmohamed M, Brodie MJ, Kwan P. Pharmacoresistance - Epidemiology, mechanisms, and impact on epilepsy treatment. Neuropharmacology. 2019 Sep 24:107790. doi: 10.1016/j.neuropharm.2019.107790.

Sokolenko E, Hudson MR, Nithianantharajah J, Jones NC. The mGluR2/3 agonist LY379268 reverses NMDA receptor antagonist effects on cortical gamma oscillations and phase coherence, but not working memory impairments, in mice. J Psychopharmacol. 2019 Oct 3:269881119875976. doi: 10.1177/0269881119875976. [Epub ahead of print] PMID: 31580222

Tan XL, Zheng P, Wright DK, Sun M, Brady RD, Liu S, McDonald SJ, Mychasiuk R, Cenap S, Jones NC, O'Brien TJ, Shultz SR. The genetic ablation of tau improves long-term, but not short-term, functional outcomes after experimental traumatic brain injury in mice. Brain Inj. 2019 Sep 16:1-9. doi: 10.1080/02699052.2019.1667539.

Wesselingh R, Butzkueven H, Buzzard K Tarlinton D, O'Brien TJ, Monif M. Innate Immunity in the Central Nervous System: A Missing Piece of the Autoimmune Encephalitis Puzzle? Front Immunol. 2019 Sep 10;10:2066. doi: 10.3389/fimmu.2019.02066. eCollection 2019.


Peninsula Clinical School

Phan R, Hunter-Smith DJ, Rozen WM.The use of Patient Reported Outcome Measures in assessing patient outcomes when comparing autologous to alloplastic breast reconstruction: a systematic review. Gland Surg. 2019 Aug;8(4):452-460. doi: 10.21037/gs.2019.07.04.


Department of Surgery

Maharaj AD, Holland JF, Scarborough RO, Evans SM, Ioannou LJ, Brown W, Croagh DG, Pilgrim CHC, Kench JG, Lipton LR, Leong T, McNeil JJ, Nikfarjam M, Aly A, Burton PR, Cashin PA, Chu J, Duong CP, Evans P, Goldstein D, Haydon A, Hii MW, Knowles BPF, Merrett ND, Michael M, Neale RE, Philip J, Porter IWT, Smith M, Spillane J, Tagkalidis PP, Zalcberg JR. The Upper Gastrointestinal Cancer Registry (UGICR): a clinical quality registry to monitor and improve care in upper gastrointestinal cancers. BMJ Open. 2019 Sep 30;9(9):e031434. doi: 10.1136/bmjopen-2019-031434.

Taylor JW, Soeyland K, Ball C, Lee JC, Serpell J. Changes in Tracheal Tube Cuff Pressure and Recurrent Laryngeal Nerve Conductivity During Thyroid Surgery. World J Surg. 2019 Sep 24. doi: 10.1007/s00268-019-05185-7. [Epub ahead of print]