3-9 March 2021 Central Clinical School recent publications

Can a diet rich in food containing prebiotic fibre lead to a
reduction in the risk of developing diabetes complications
 in individuals with type 2 diabetes?
Diabetes researchers Melinda Coughlan and Matt Snelson
are teasing out more detail: Study

They have also published a study on the effect on mice
of a high protein diet: it caused inflammation, potentially
damaging the kidneys.

Recent publications featuring research as notified by PubMed during 2-9 Mar 2021 from Central Clinical School affiliated researchers in the following departments. The below is not a comprehensive list. Most recent validated publications for the school and departments can be seen on their publications pages, linked to from the headings below. Otherwise, read down the entry for this week's notifications.

• Anaesthesia and Perioperative Medicine
• Gastroenterology
• Immunology and Pathology
• Infectious Diseases
• Medicine (including AIRmed)
• Melbourne Sexual Health Centre
• Monash Alfred Psychiatry research centre
• Neuroscience
• Peninsula Clinical School
• Psychiatry
  
• Surgery (including National Trauma Research Institute)

Department of Allergy, Immunology and Respiratory medicine

Nugraha R, Ruethers T, Johnston EB, Rolland JM, O'Hehir RE, Kamath SD, Lopata AL. Effects of Extraction Buffer on the Solubility and Immunoreactivity of the Pacific Oyster Allergens. Foods. 2021 Feb 12;10(2):409. doi: 10.3390/foods10020409. PMID: 33673192; PMCID: PMC7917601.


Australian Centre for Blood Diseases

Larson RA, Mandrekar SJ, Huebner LJ, ..., Wei AH, ..., Stone RM. Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY trial. Leukemia. 2021 Mar 2. doi: 10.1038/s41375-021-01179-4. Epub ahead of print. PMID: 33654204.

Vergara IA, Mintoff CP, Sandhu S, ..., Peng A, ..., Szeto P,..., Shackleton M. Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling. Nat Commun. 2021 Mar 4;12(1):1434. doi: 10.1038/s41467-021-21576-8. PMID: 33664264.

Wei AH, Ribera JM, Larson RA, ... Kantarjian H. Biomarkers associated with blinatumomab outcomes in acute lymphoblastic leukemia. Leukemia. 2021 Feb 4. doi: 10.1038/s41375-020-01089-x. Epub ahead of print. PMID: 33542479.

Yeola A, Subramanian S, Oliver RA, ..., Curtis DJ, ..., Pimanda JE. Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine. Sci Adv. 2021 Jan 13;7(3):eabd1929. doi: 10.1126/sciadv.abd1929. PMID: 33523875; PMCID: PMC7806226.


Department of Diabetes

Mazarakis N, Anderson J, Toh ZQ, Higgins RA, Do LAH, Luwor RB, Snibson KJ, Karagiannis TC, Licciardi PV. Examination of Novel Immunomodulatory Effects of L-Sulforaphane. Nutrients. 2021 Feb 12;13(2):602. doi: 10.3390/nu13020602. PMID: 33673203; PMCID: PMC7917832.

Snelson M, Clarke RE, Nguyen TV, Penfold SA, Forbes JM, Tan SM, Coughlan MT. Long Term High Protein Diet Feeding Alters the Microbiome and Increases Intestinal Permeability, Systemic Inflammation and Kidney Injury in Mice. Mol Nutr Food Res. 2021 Feb 6:e2000851. doi: 10.1002/mnfr.202000851. Epub ahead of print. PMID: 33547877.

Snelson M, de Pasquale C, Ekinci EI, Coughlan MT. Gut microbiome, prebiotics, intestinal permeability and diabetes complications. Best Pract Res Clin Endocrinol Metab. 2021 Feb 17:101507. doi: 10.1016/j.beem.2021.101507. Epub ahead of print. PMID: 33642218.


Department of Gastroenterology

Ardalan ZS, Sparrow MP. A pragmatic stepwise approach to the diagnosis and management of refractory acute pouchitis. Expert Opin Pharmacother. 2021 Feb 4:1-3. doi: 10.1080/14656566.2021.1882422. Epub ahead of print. PMID: 33538185.

Department of Infectious Diseases

Ashok A, Hoy J, Spelman D, McMahon J, Pai Mangalore R. Successful treatment of disseminated Mycobacterium simiae infection in a patient with advanced HIV. AIDS. 2021 Jan 1;35(1):157-158. doi: 10.1097/QAD.0000000000002702. PMID: 33273186.

Jokanovic N, Haines T, Cheng AC, Holt KE, Hilmer SN, Jeon YH, Stewardson AJ, Stuart RL, Spelman T, Peel TN, Peleg AY; START Trial Group. Multicentre stepped-wedge cluster randomised controlled trial of an antimicrobial stewardship programme in residential aged care: protocol for the START trial. BMJ Open. 2021 Mar 2;11(3):e046142. doi: 10.1136/bmjopen-2020-046142. PMID: 33653766.

Liu FF, Hall V, Cronin KM, Nair AP, Mclean CA, Hoy JF. 'Peeling back the onion layers': the challenge of HIV-associated multicentric Castleman's disease. AIDS. 2021 Jan 1;35(1):159-161. doi: 10.1097/QAD.0000000000002705. PMID: 33273187.

McManus H, Callander D, Asselin J, McMahon J, Hoy JF, Templeton DJ, Fairley CK, ..., Guy RJ. A New Method for Estimating the Incidence of Infectious Diseases. Am J Epidemiol. 2021 Feb 4:kwab014. doi: 10.1093/aje/kwab014. Epub ahead of print. PMID: 33534904.


Department of Medicine - Alfred and Peninsula

Eliakundu AL, Cadilhac DA, Kim J, Andrew NE, Bladin CF, Grimley R, Dewey HM, Donnan GA, Hill K, Levi CR, Middleton S, Anderson CS, Lannin NA, Kilkenny MF; AuSCR consortium partners, Stroke123 investigators. Factors associated with arrival by ambulance for patients with stroke: a multicentre, national data linkage study. Australas Emerg Care. 2021 Feb 25:S2588-994X(21)00002-6. doi: 10.1016/j.auec.2021.01.002. Epub ahead of print. PMID: 33642255.

Hamblin PS, Wong R, Bach LA. Sodium-glucose cotransporter type 2 inhibitors: managing the small but critical risk of diabetic ketoacidosis. Med J Aust. 2021 Feb;214(2):94-94.e1. doi: 10.5694/mja2.50898. Epub 2020 Dec 21. PMID: 33349919.


Melbourne Sexual Health Centre

Choi KWY, Choi EPH, Chow EPF, Wan EYF, Wong WCW, Wong JYH, Fong DYT. The Experience of Using Dating Applications for Sexual Hook-Ups: A Qualitative Exploration among HIV-Negative Men Who Have Sex With Men in Hong Kong. J Sex Res. 2021 Mar 3:1-10. doi: 10.1080/00224499.2021.1886227. Epub ahead of print. PMID: 33656408.
https://pubmed.ncbi.nlm.nih.gov/33656408/

Chow EPF, Williamson DA, Hocking JS, Law MG, Maddaford K, Bradshaw CS, McNulty A, Templeton DJ, Moore R, Murray GL, Danielewski JA, Wigan R, Chen MY, Guy RJ, Zhang L, Donovan B, Grulich AE, Kaldor JM, Whiley DM, Cornelisse VJ, Howden BP, Lewis DA, Read TRH, Fairley CK. Antiseptic mouthwash for gonorrhoea prevention (OMEGA): a randomised, double-blind, parallel-group, multicentre trial. Lancet Infect Dis. 2021 Mar 4:S1473-3099(20)30704-0. doi: 10.1016/S1473-3099(20)30704-0. Epub ahead of print. PMID: 33676595.
https://pubmed.ncbi.nlm.nih.gov/33676595/

Chow EPF, Ong JJ, Denham I, Fairley CK. HIV Testing and Diagnoses During the COVID-19 Pandemic in Melbourne, Australia. J Acquir Immune Defic Syndr. 2021 Apr 1;86(4):e114-e115. doi: 10.1097/QAI.0000000000002604. PMID: 33346567; PMCID: PMC7901531.
https://pubmed.ncbi.nlm.nih.gov/33346567/

Green K, Schmidt HA, Vallely AJ, Zhang L, Kelly-Hanku A, Janamnuaysook R, Ong JJ. Ending AIDS in the Asia-Pacific region by 2030: are we on track? Policy, epidemiological and intervention insights. Sex Health. 2021 Mar;18(1):1-4. doi: 10.1071/SH20226. PMID: 33663685.
https://pubmed.ncbi.nlm.nih.gov/33663685/

Lee DYJ, Ashcroft MM, Chow EPF, Sait M, De Petra V, Tschaepe M, Lange S, Taiaroa G, Bradshaw CS, Whiley DM, Fairley CK, Howden BP, Chen MY, Pasricha S, Williamson DA. Reflex detection of ciprofloxacin resistance in Neisseria gonorrhoeae using the SpeeDx ResistancePlus® GC assay. J Clin Microbiol. 2021 Mar 3:JCM.00089-21. doi: 10.1128/JCM.00089-21. Epub ahead of print. PMID: 33658263.
https://pubmed.ncbi.nlm.nih.gov/33658263/

Peel J, Chow EPF, Denham I, Schmidt T, Buchanan A, Fairley C, Williamson DA, Bissessor M, Chen MY. Clinical presentation of incident syphilis among men who have sex with men taking HIV Pre-Exposure Prophylaxis in Melbourne, Australia. Clin Infect Dis. 2021 Feb 1:ciab052. doi: 10.1093/cid/ciab052. Epub ahead of print. PMID: 33522575.
https://pubmed.ncbi.nlm.nih.gov/33522575/

Ratnappuli A, Bissessor M, Arumugam S, Williamson DA, Chow EPF, Fairley CK, Ong JJ, De Petra V, Chen MY. Culture obtained from urethral swab of asymptomatic men who screen positive for Neisseria gonorrhoeae by urine nucleic acid amplification testing. Sex Transm Infect. 2021 Feb 1:sextrans-2020-054690. doi: 10.1136/sextrans-2020-054690. Epub ahead of print. PMID: 33526591.
https://pubmed.ncbi.nlm.nih.gov/33526591/

Ratten LK, Plummer EL, Murray GL, Danielewski J, Fairley CK, Garland SM, Hocking JS, Tachedjian G, Chow E, Bradshaw CS, Vodstrcil LA. Sex is associated with the persistence of non-optimal vaginal microbiota following treatment for bacterial vaginosis: a prospective cohort study. BJOG. 2021 Mar;128(4):756-767. doi: 10.1111/1471-0528.16430. Epub 2020 Aug 16. PMID: 33480468.
https://pubmed.ncbi.nlm.nih.gov/33480468/

Shen M, Zu J, Fairley CK, Pagán JA, Ferket B, Liu B, Yi SS, Chambers E, Li G, Guo Y, Rong L, Xiao Y, Zhuang G, Zebrowski A, Carr BG, Li Y, Zhang L. Effects of New York's Executive Order on Face Mask Use on COVID-19 Infections and Mortality: A Modeling Study. J Urban Health. 2021 Mar 1:1–8. doi: 10.1007/s11524-021-00517-2. Epub ahead of print. PMID: 33649905; PMCID: PMC7919630.
https://pubmed.ncbi.nlm.nih.gov/33649905/

"Our study provides public health practitioners and policymakers with evidence on the importance of implementing face mask policies in local areas as early as possible to control the spread of COVID-19 and reduce mortality."

Department of Neuroscience

Bakhuraysah MM, Theotokis P, Lee JY, Alrehaili AA, Aui PM, Figgett WA, Azari MF, Abou-Afech JP, Mackay F, Siatskas C, Alderuccio F, Strittmatter SM, Grigoriadis N, Petratos S. B-cells expressing NgR1 and NgR3 are localized to EAE-induced inflammatory infiltrates and are stimulated by BAFF. Sci Rep. 2021 Feb 3;11(1):2890. doi: 10.1038/s41598-021-82346-6. PMID: 33536561; PMCID: PMC7858582.
https://pubmed.ncbi.nlm.nih.gov/33536561/

Broadley J, Wesselingh R, Seneviratne U, Kyndt C, Beech P, Buzzard K, Nesbitt C, D'Souza W, Brodtmann A, Kalincik T, Butzkueven H, O'Brien TJ, Monif M; Australian Autoimmune Encephalitis Consortium. Peripheral Immune Cell Ratios and Clinical Outcomes in Seropositive Autoimmune Encephalitis: A Study by the Australian Autoimmune Encephalitis Consortium. Front Immunol. 2021 Jan 14;11:597858. doi: 10.3389/fimmu.2020.597858. PMID: 33519810; PMCID: PMC7840591.
https://pubmed.ncbi.nlm.nih.gov/33519810/

Honybun E, Thwaites R, Malpas CB, Rayner G, Anderson A, Graham J, Hitchcock A, O'Brien TJ, Vajda FJE, Perucca P. Prenatal valproate exposure and adverse neurodevelopmental outcomes: Does sex matter? Epilepsia. 2021 Mar;62(3):709-719. doi: 10.1111/epi.16827. Epub 2021 Feb 5. PMID: 33547648.
https://pubmed.ncbi.nlm.nih.gov/33547648/

Strik M, Shanahan CJ, van der Walt A, Boonstra FMC, Glarin R, Galea MP, Kilpatrick TJ, Geurts JJG, Cleary JO, Schoonheim MM, Kolbe SC. Functional correlates of motor control impairments in multiple sclerosis: A 7 Tesla task functional MRI study. Hum Brain Mapp. 2021 Mar 5. doi: 10.1002/hbm.25389. Epub ahead of print. PMID: 33666314.
https://pubmed.ncbi.nlm.nih.gov/33666314/

Vazquez B, Tomson T, Dobrinsky C, Schuck E, O'Brien TJ. Perampanel and pregnancy. Epilepsia. 2021 Mar;62(3):698-708. doi: 10.1111/epi.16821. PMID: 33666943.
https://pubmed.ncbi.nlm.nih.gov/33666943/


Department of Psychiatry

Cash RFH, Cocchi L, Lv J, Wu Y, Fitzgerald PB, Zalesky A. Personalized connectivity-guided DLPFC-TMS for depression: Advancing computational feasibility, precision and reproducibility. Hum Brain Mapp. 2021 Feb 5. doi: 10.1002/hbm.25330. Epub ahead of print. PMID: 33544411.
https://pubmed.ncbi.nlm.nih.gov/33544411/


Department of Surgery

Baroun-Agob L, Liew S, Gabbe B. Outcomes of surgical site infections following spinal column trauma. ANZ J Surg. 2021 Feb 5. doi: 10.1111/ans.16578. Epub ahead of print. PMID: 33543581.
https://pubmed.ncbi.nlm.nih.gov/33543581/

Lim G, Johari Y, Ooi G, Playfair J, Laurie C, Hebbard G, Brown W, Burton P. Diagnostic Criteria for Gastro-esophageal Reflux Following Sleeve Gastrectomy. Obes Surg. 2021 Jan 25. doi: 10.1007/s11695-020-05152-5. Epub ahead of print. PMID: 33491160.

https://pubmed.ncbi.nlm.nih.gov/33491160/

Lourensz K, Loh D, Burton P. Post-oesophagectomy chyle leak presenting as a pleuro-enteral lymphatic shunt via the gastric conduit. ANZ J Surg. 2021 Mar 2. doi: 10.1111/ans.16696. Epub ahead of print. PMID: 33650750.
https://pubmed.ncbi.nlm.nih.gov/33650750/

Qu Y, Peleg AY, McGiffin D. Ventricular Assist Device-Specific Infections. J Clin Med. 2021 Jan 25;10(3):453. doi: 10.3390/jcm10030453. PMID: 33503891; PMCID: PMC7866069.
https://pubmed.ncbi.nlm.nih.gov/33503891/

Tan JL, Papa N, Hanegbi U, Snow R, Grummet J, Mann S, Cuthbertson A, Frydenberg M, Moon D. Predictors of erectile dysfunction after transperineal template prostate biopsy. Investig Clin Urol. 2021 Mar;62(2):159-165. doi: 10.4111/icu.20200236. PMID: 33660442.
https://pubmed.ncbi.nlm.nih.gov/33660442/

Wagner K, Jassal K, Lee JC, Ban EJ, Cameron R, Serpell J. Challenges in diagnosis and management of a spiradenocarcinoma: a comprehensive literature review. ANZ J Surg. 2021 Feb 1. doi: 10.1111/ans.16626. Epub ahead of print. PMID: 33522696.
https://pubmed.ncbi.nlm.nih.gov/33522696/