16-29 Nov 2021 Central Clinical School recent publications

Is the FODMAP diet more than just a symptomatic therapy?
BMJ commentary by Peter Gibson and Emma Halmos

Recent publications featuring research as notified by PubMed during 16-29 Nov 2021 from Central Clinical School affiliated researchers in the following departments. The below is not a comprehensive list. The most recent validated publications for the school and departments can be seen on their publications pages, linked to from the headings below. Otherwise, read down the entry for recent notifications.

• Anaesthesiology and Perioperative Medicine
• Australian Centre for Blood Diseases
• Diabetes
  
• Gastroenterology
• Immunology and Pathology
• Infectious Diseases
• Medicine (including Alfred and Peninsula)
• Melbourne Sexual Health Centre
• Neuroscience
• Psychiatry
  
• Surgery (including National Trauma Research Institute)
  

Department of Anaesthesiology and Perioperative Medicine

Evered LA, Chan MTV, Han R, Chu MHM, Cheng BP, Scott DA, Pryor KO, Sessler DI, Veselis R, Frampton C, Sumner M, Ayeni A, Myles PS, Campbell D, Leslie K, Short TG. Anaesthetic depth and delirium after major surgery: a randomised clinical trial. Br J Anaesth. 2021 Nov;127(5):704-712. doi: 10.1016/j.bja.2021.07.021. Epub 2021 Aug 28. PMID: 34465469; PMCID: PMC8579421.
https://pubmed.ncbi.nlm.nih.gov/34465469/

Ferguson MT, Kusre S, Myles PS. Minimal clinically important difference in days at home up to 30 days after surgery. Anaesthesia. 2021 Nov 19. doi: 10.1111/anae.15623. Epub ahead of print. PMID: 34797923.
https://pubmed.ncbi.nlm.nih.gov/34797923/

Fernando H, Nehme Z, Peter K, Bernard S, Stephenson M, Bray JE, Myles PS, Stub R, Cameron P, Ellims AH, Taylor AJ, Kaye DM, Smith K, Stub D. Association between pre-hospital chest pain severity and myocardial injury in ST elevation myocardial infarction: A post-hoc analysis of the AVOID study. Int J Cardiol Heart Vasc. 2021 Nov 8;37:100899. doi: 10.1016/j.ijcha.2021.100899. PMID: 34815999; PMCID: PMC8591354.
https://pubmed.ncbi.nlm.nih.gov/34815999/

Hodgson CL, Higgins AM, Bailey MJ, ..., Myles PS, ..., Neto AS; COVID-Recovery Study Investigators and the ANZICS Clinical Trials Group. The impact of COVID-19 critical illness on new disability, functional outcomes and return to work at 6 months: a prospective cohort study. Crit Care. 2021 Nov 8;25(1):382. doi: 10.1186/s13054-021-03794-0. PMID: 34749756; PMCID: PMC8575157.
https://pubmed.ncbi.nlm.nih.gov/34749756/


Australian Centre for Blood Diseases

de Maat S, Clark C, Barendrecht AD, Smits S, van Kleef ND, El Otmani H, Waning M, van Moorsel MVA, Szardenings M, Delaroque N, Vercruysse K, Urbanus RT, Sebastian S, Lenting PJ, Hagemeyer CE, Renné T, Vanhoorelbeke K, Tersteeg C, Maas C. Microlyse; a thrombolytic agent that targets VWF for clearance of microvascular thrombosis. Blood. 2021 Nov 9:blood.2021011776. doi: 10.1182/blood.2021011776. Epub ahead of print. PMID: 34752601.
https://pubmed.ncbi.nlm.nih.gov/34752601/

Nguyen PC, Manos K, Fong CY, Schwarer AP, Tiong IS, Wei AH, Kliman D, Curtis DJ. Outcomes of non-myeloablative allogeneic stem cell transplant in older patients with acute myeloid leukaemia in first remission. Intern Med J. 2021 Nov;51(11):1954-1958. doi: 10.1111/imj.15564. PMID: 34796631.
https://pubmed.ncbi.nlm.nih.gov/34796631/

Wang J, Farkas C, Benyoucef A, Carmichael C, Haigh K, Wong N, Huylebroeck D, Stemmler MP, Brabletz S, Brabletz T, Nefzger CM, Goossens S, Berx G, Polo JM, Haigh JJ. Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity. PLoS Biol. 2021 Sep 22;19(9):e3001394. doi: 10.1371/journal.pbio.3001394. PMID: 34550965; PMCID: PMC8489726.
https://pubmed.ncbi.nlm.nih.gov/34550965/


Department of Diabetes

Bilu C, Frolinger-Ashkenazi T, Einat H, Zimmet P, Bishko Y, Halperin D, Kronfeld-Schor N. Effects of photoperiod and diet on BDNF daily rhythms in diurnal sand rats. Behav Brain Res. 2021 Nov 19;418:113666. doi: 10.1016/j.bbr.2021.113666. Epub ahead of print. PMID: 34808195.
https://pubmed.ncbi.nlm.nih.gov/34808195/

Riddy DM, Kammoun HL, Murphy AJ, Bosnyak-Gladovic S, De la Fuente Gonzalez R, Merlin J, Ziemann M, Fabb S, Pierce TL, Diepenhorst N, Rueda P, El-Osta A, Gautier JF, Venteclef N, Charman WN, Christopoulos A, Sexton PM, Summers RJ, Febbraio MA, Delerive P, Langmead CJ. Deletion of GPR21 improves glucose homeostasis and inhibits the CCL2-CCR2 axis by divergent mechanisms. BMJ Open Diabetes Res Care. 2021 Nov;9(2):e002285. doi: 10.1136/bmjdrc-2021-002285. PMID: 34782333; PMCID: PMC8593704.
https://pubmed.ncbi.nlm.nih.gov/34782333/

Tan SM, Snelson M, Østergaard JA, Coughlan MT. The complement pathway: New insights into immunometabolic signalling in diabetic kidney disease. Antioxid Redox Signal. 2021 Nov 22. doi: 10.1089/ars.2021.0125. Epub ahead of print. PMID: 34806406.
https://pubmed.ncbi.nlm.nih.gov/34806406/


Department of Gastroenterology

Gibson PR, Halmos EP. The FODMAP diet: more than just a symptomatic therapy? Gut. 2021 Nov 22:gutjnl-2021-326284. doi: 10.1136/gutjnl-2021-326284. Epub ahead of print. PMID: 34810233.
https://pubmed.ncbi.nlm.nih.gov/34810233/

Harney BL, Whitton B, Paige E, Brereton R, Weiss R, Membrey D, Wade AJ, Iser D, Kemp W, Roberts SK, Spelman T, Sacks-Davis R, Hellard ME, Doyle JS. A multi-site, nurse-coordinated hepatitis C model of care in primary care and community services in Melbourne, Australia. Liver Int. 2021 Nov 25. doi: 10.1111/liv.15107. Epub ahead of print. PMID: 34821021.
https://pubmed.ncbi.nlm.nih.gov/34821021/


Department of Infectious Diseases

Curtis SJ, Rathnayaka A, Wu F, Al Mamun A, Spiers C, Bingham G, Lau CL, Peleg AY, Yuce MR, Stewardson AJ. Feasibility of Bluetooth Low Energy wearable tags to quantify healthcare worker proximity networks and patient close contact: A pilot study. Infect Dis Health. 2021 Nov 19:S2468-0451(21)00098-5. doi: 10.1016/j.idh.2021.10.004. Epub ahead of print. PMID: 34810151.
https://pubmed.ncbi.nlm.nih.gov/34810151/


Department of Medicine

Collyer TA, Athanasopoulos G, Srikanth V, Tiruvoipati R, Matthews C, Mcinnes N, Menon S, Dowling J, Braun G, Krivitsky TA, Cooper H, Andrew NE. Impact of COVID-19 lockdowns on hospital presentations and admissions in the context of low community transmission: evidence from time series analysis in Melbourne, Australia. J Epidemiol Community Health. 2021 Nov 15:jech-2021-217010. doi: 10.1136/jech-2021-217010. Epub ahead of print. PMID: 34782421; PMCID: PMC8595051.
https://pubmed.ncbi.nlm.nih.gov/34782421/

Moran C, Than S, Callisaya M, Beare R, Srikanth V. New Horizons - Cognitive dysfunction associated with type 2 diabetes. J Clin Endocrinol Metab. 2021 Nov 12:dgab797. doi: 10.1210/clinem/dgab797. Epub ahead of print. PMID: 34788847.
https://pubmed.ncbi.nlm.nih.gov/34788847/

Paynter JA, Tobin V, Hurst LC, Badalamente MA, Hunter-Smith DJ, Rozen WM. Antithrombotic Use with Collagenase Clostridium Histolyticum Injection to Treat Dupuytren Disease. J Hand Surg Asian Pac Vol. 2021 Dec;26(4):599-610. doi: 10.1142/S2424835521500570. PMID: 34789118.
https://pubmed.ncbi.nlm.nih.gov/34789118/

Ratnayake H, Crabtree A, Hunter P, Parikh S, Tay B, Anthonisz B, Moran C. Evaluation of a dedicated outpatient hip fracture clinic. Australas J Ageing. 2021 Nov 27. doi: 10.1111/ajag.13020. Epub ahead of print. PMID: 34837298.
https://pubmed.ncbi.nlm.nih.gov/34837298/

Rehman S, Phan HT, Reeves MJ, Thrift AG, Cadilhac DA, Sturm J, Breslin M, Callisaya ML, Vemmos K, Parmar P, Krishnamurthi RV, Barker-Collo S, Feigin V, Chausson N, Olindo S, Cabral NL, Carolei A, Marini C, Degan D, Sacco S, Correia M, Appelros P, Kõrv J, Vibo R, Minelli C, Sposato L, Pandian JD, Kaur P, Azarpazhooh MR, Morovatdar N, Gall S. Case-Fatality and Functional Outcome after Subarachnoid Hemorrhage (SAH) in INternational STRoke oUtComes sTudy (INSTRUCT). J Stroke Cerebrovasc Dis. 2021 Nov 15;31(1):106201. doi: 10.1016/j.jstrokecerebrovasdis.2021.106201. Epub ahead of print. PMID: 34794031.
https://pubmed.ncbi.nlm.nih.gov/34794031/

Snowdon DA, Vincent P, Callisaya ML, Collyer TA, Wang YT, Taylor NF. Feasibility of allied health assistant management of people with acute hip fracture: protocol for a feasibility randomised controlled trial. BMJ Open. 2021 Nov 23;11(11):e054298. doi: 10.1136/bmjopen-2021-054298. PMID: 34815289.
https://pubmed.ncbi.nlm.nih.gov/34815289/

Tiruvoipati R, Gupta S, Haji K. COVID-19 Is Not Comparable to H1N1 Influenza. Ann Am Thorac Soc. 2021 Nov 24. doi: 10.1513/AnnalsATS.202110-1097LE. Epub ahead of print. PMID: 34818143.
https://pubmed.ncbi.nlm.nih.gov/34818143/


Melbourne Sexual Health Centre

Aboud L, Xu Y, Chow EPF, Wi T, Baggaley R, Mello MB, Fairley CK, Ong JJ. Diagnostic accuracy of pooling urine, anorectal, and oropharyngeal specimens for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae: a systematic review and meta-analysis. BMC Med. 2021 Nov 25;19(1):285. doi: 10.1186/s12916-021-02160-9. PMID: 34819068; PMCID: PMC8614052.
https://pubmed.ncbi.nlm.nih.gov/34819068

Hui BB, Hocking JS, Braat S, Donovan B, Fairley CK, Guy R, Spark S, Yeung A, Low N, Regan D. Intensified partner notification and repeat testing can improve the effectiveness of screening in reducing Chlamydia trachomatis prevalence: a mathematical modelling study. Sex Transm Infect. 2021 Nov 23:sextrans-2021-055220. doi: 10.1136/sextrans-2021-055220. Epub ahead of print. PMID: 34815362.
https://pubmed.ncbi.nlm.nih.gov/34815362/

Iwelunmor J, Tucker JD, Obiezu-Umeh C, Gbaja-Biamila T, Oladele D, Nwaozuru U, Musa AZ, Airhihenbuwa CO, Muessig K, Rosenberg N, BeLue R, Xian H, Conserve DF, Ong JJ, Zhang L, Curley J, Nkengasong S, Mason S, Tang W, Bayus B, Ogedegbe G, Ezechi O. The 4 Youth by Youth (4YBY) pragmatic trial to enhance HIV self-testing uptake and sustainability: Study protocol in Nigeria. Contemp Clin Trials. 2021 Nov 17:106628. doi: 10.1016/j.cct.2021.106628. Epub ahead of print. PMID: 34800699.
https://pubmed.ncbi.nlm.nih.gov/34800699/

Jing F, Zhang Q, Ong JJ, Xie Y, Ni Y, Cheng M, Huang S, Zhou Y, Tang W. Optimal resource allocation in HIV self-testing secondary distribution among Chinese MSM: data-driven integer programming models. Philos Trans A Math Phys Eng Sci. 2022 Jan 10;380(2214):20210128. doi: 10.1098/rsta.2021.0128. Epub 2021 Nov 22. PMID: 34802269.
https://pubmed.ncbi.nlm.nih.gov/34802269/

Ong JJ, Xiong M, Tucker JD, Wang Y, Smith MK, Tang W, Fu H, Zheng H, Yang B, Wang C. Sexualized Drug Use Among Female Sex Workers from Eight Cities in China: A Cross-Sectional Study. Arch Sex Behav. 2021 Nov 16:1–10. doi: 10.1007/s10508-021-02117-2. Epub ahead of print. PMID: 34786656; PMCID: PMC8594644.
https://pubmed.ncbi.nlm.nih.gov/34786656/

Traeger MW, Murphy D, Ryan KE, Asselin J, Cornelisse VJ, Wilkinson AL, Hellard ME, Wright EJ, Stoové MA. Latent Class Analysis of Sexual Behaviours and Attitudes to Sexually Transmitted Infections Among Gay and Bisexual Men Using PrEP. AIDS Behav. 2021 Nov 15. doi: 10.1007/s10461-021-03529-w. Epub ahead of print. PMID: 34782934.
https://pubmed.ncbi.nlm.nih.gov/34782934/

Zou Z, Fairley CK, Shen M, Scott N, Xu X, Li Z, Li R, Zhuang G, Zhang L. Critical timing and extent of public health interventions to control outbreaks dominated by SARS-CoV-2 variants in Australia: a mathematical modelling study. Int J Infect Dis. 2021 Nov 17:S1201-9712(21)00870-5. doi: 10.1016/j.ijid.2021.11.024. Epub ahead of print. PMID: 34800688; PMCID: PMC8598259.
https://pubmed.ncbi.nlm.nih.gov/34800688/


Department of Neuroscience

Chu E, Mychasiuk R, Hibbs ML, Semple BD. Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation. J Neuroinflammation. 2021 Nov 27;18(1):276. doi: 10.1186/s12974-021-02325-6. PMID: 34838047; PMCID: PMC8627624.
https://pubmed.ncbi.nlm.nih.gov/34838047/

Ibrahim, O., Sutherland, H. G., Lea, R. A., Nasrallah, F., Maksemous, N., Smith, R. A., Haupt, L. M., & Griffiths, L. R. (2021). Discriminating head trauma outcomes using machine learning and genomics. Journal of molecular medicine (Berlin, Germany), 10.1007/s00109-021-02158-z. Advance online publication. https://doi.org/10.1007/s00109-021-02158-z

Mariajoseph, F. P., Rewell, S. S., O'Brien, T. J., Semple, B. D., & Antonic-Baker, A. (2021). Incidence of post-traumatic epilepsy following paediatric traumatic brain injury: protocol for systematic review and meta-analysis. BMJ open, 11(11), e054034. https://doi.org/10.1136/bmjopen-2021-054034

Li R, Yuan X, Radfar M, Marendy P, Ni W, O'Brien TJ, Casillas-Espinosa PM. Graph Signal Processing, Graph Neural Network and Graph Learning on Biological Data: A Systematic Review. IEEE Rev Biomed Eng. 2021, doi: https://doi.org/10.1109/rbme.2021.3122522

Merlo D, Tomas Kalincik, Chao Zhu, Melissa Gresle, Jeannette Lechner-Scott, Trevor Kilpatrick, Michael Barnett, Bruce Taylor, Katherine Buzzard, David Darby, Helmut Butzkueven, Anneke van der Walt. Subjective versus objective performance in people with multiple sclerosis using the MSReactor computerised cognitive tests. Multiple Sclerosis and Related Disorders, 2021; 103393, https://doi.org/10.1016/j.msard.2021.103393

O'Brien TJ, Fenton K, Sidahmed A, Barbour A, Harralson AF. Race and Drug Toxicity: A Study of Three Cardiovascular Drugs with Strong Pharmacogenetic Recommendations. J Pers Med. 2021 Nov 18;11(11):1226. doi: 10.3390/jpm11111226. PMID: 34834577; PMCID: PMC8622254.
https://pubmed.ncbi.nlm.nih.gov/34834577/

Sharma R, Casillas-Espinosa PM, Dill LK, Rewell SSJ, Hudson MR, O'Brien TJ, Shultz SR, Semple BD. Pediatric traumatic brain injury and a subsequent transient immune challenge independently influenced chronic outcomes in male mice. Brain Behav Immun. 2021 Nov 19;100:29-47. doi: 10.1016/j.bbi.2021.11.013. Epub ahead of print. PMID: 34808288.
https://pubmed.ncbi.nlm.nih.gov/34808288/

Rasheed K, Qadir J, O'Brien TJ, Kuhlmann L, Razi A. A Generative Model to Synthesize EEG Data for Epileptic Seizure Prediction. IEEE Trans Neural Syst Rehabil Eng. 2021;29:2322-2332. doi: 10.1109/TNSRE.2021.3125023. Epub 2021 Nov 10. PMID: 34727036; PMCID: PMC8592500.
https://pubmed.ncbi.nlm.nih.gov/34727036/

Urrutia-Cabrera D, Liou RH, Wang JH, Chan J, Hung SS, Hewitt AW, Martin KR, Edwards TL, Kwan P, Wong RC. Comparative analysis of loop-mediated isothermal amplification (LAMP)-based assays for rapid detection of SARS-CoV-2 genes. Sci Rep. 2021 Nov 18;11(1):22493. doi: 10.1038/s41598-021-01472-3. PMID: 34795308; PMCID: PMC8602269.
https://pubmed.ncbi.nlm.nih.gov/34795308/


Department of Psychiatry - Central

Hoy KE, Emonson MRL, Bailey NW, Humble G, Coyle H, Rogers C, Fitzgerald PB. Investigating Neurophysiological Markers of Symptom Severity in Alzheimer's Disease. J Alzheimers Dis. 2021 Nov 18. doi: 10.3233/JAD-210401. Epub ahead of print. PMID: 34806601.
https://pubmed.ncbi.nlm.nih.gov/34806601/

Tang VM, Blumberger DM, Hill AT, Weissman CR, Voineskos D, Rajji TK, Downar J, Knyahnytska Y, Mulsant BH, Fitzgerald PB, Daskalakis ZJ. Magnetic Seizure Therapy for the Treatment of Suicidality in Bipolar Depression. Biol Psychiatry. 2021 Nov 15;90(10):e51-e53. doi: 10.1016/j.biopsych.2020.09.020. Epub 2020 Nov 7. PMID: 33172609.
https://pubmed.ncbi.nlm.nih.gov/33172609/

Williams ML, Korevaar D, Harvey R, Fitzgerald PB, Liknaitzky P, O'Carroll S, Puspanathan P, Ross M, Strauss N, Bennett-Levy J. Translating Psychedelic Therapies From Clinical Trials to Community Clinics: Building Bridges and Addressing Potential Challenges Ahead. Front Psychiatry. 2021 Nov 4;12:737738. doi: 10.3389/fpsyt.2021.737738. PMID: 34803761; PMCID: PMC8599345.
https://pubmed.ncbi.nlm.nih.gov/34803761/


Department of Respiratory Research@Alfred

Cox NS, Lahham A, McDonald CF, Mahal A, O'Halloran P, Hepworth G, Spencer L, McNamara RJ, Bondarenko J, Macdonald H, Gavin S, Burge AT, Le Maitre C, Ringin C, Webb E, Nichols A, Tsai LL, Luxton N, van Hilten S, Santos M, Crute H, Byrne M, Boursinos H, Broe J, Corbett M, Marceau T, Warrick B, Boote C, Melinz J, Holland AE. Home-based pulmonary rehabilitation early after hospitalisation in COPD (early HomeBase): protocol for a randomised controlled trial. BMJ Open Respir Res. 2021 Nov;8(1):e001107. doi: 10.1136/bmjresp-2021-001107. PMID: 34819323.
https://pubmed.ncbi.nlm.nih.gov/34819323/

Disler R, Cui Y, Luckett T, Donesky D, Irving L, Currow DC, Smallwood N. Respiratory Nurses Have Positive Attitudes But Lack Confidence in Advance Care Planning for Chronic Obstructive Pulmonary Disease: Online Survey. J Hosp Palliat Nurs. 2021 Oct 1;23(5):442-454. doi: 10.1097/NJH.0000000000000778. PMID: 34369423.
https://pubmed.ncbi.nlm.nih.gov/34369423/

Khor YH. Pulmonary fibrosis: Where from and where to? Respirology. 2021 Sep;26(9):837-839. doi: 10.1111/resp.14125. Epub 2021 Aug 1. PMID: 34337823.
https://pubmed.ncbi.nlm.nih.gov/34337823/

Khor YH, Ryerson CJ, Landry SA, Howard ME, Churchward TJ, Edwards BA, Hamilton GS, Joosten SA. Interstitial lung disease and obstructive sleep apnea. Sleep Med Rev. 2021 Aug;58:101442. doi: 10.1016/j.smrv.2021.101442. Epub 2021 Jan 22. PMID: 33561604.
https://pubmed.ncbi.nlm.nih.gov/33561604/

Kotsimbos T, Kaye D, Keating D. Pulmonary arterial hypertension and CFTR: the paradox of going forward by tacking sideways! Eur Respir J. 2021 Nov 25;58(5):2101839. doi: 10.1183/13993003.01839-2021. PMID: 34824129.
https://pubmed.ncbi.nlm.nih.gov/34824129/

Lahham A, Holland AE. The Need for Expanding Pulmonary Rehabilitation Services. Life (Basel). 2021 Nov 15;11(11):1236. doi: 10.3390/life11111236. PMID: 34833112; PMCID: PMC8622005.
https://pubmed.ncbi.nlm.nih.gov/34833112/

Tikellis G, Corte TJ, Teoh AKY, Glaspole IN, Macansh S, Holland AE. Barriers and facilitators to best care for idiopathic pulmonary fibrosis in Australia. Respirology. 2021 Nov 15. doi: 10.1111/resp.14185. Epub ahead of print. PMID: 34783108.
https://pubmed.ncbi.nlm.nih.gov/34783108/


Department of Surgery & National Trauma Research Institute

Awoke MA, Earnest A, Joham AE, Hodge AM, Teede HJ, Brown WJ, Moran LJ. Weight gain and lifestyle factors in women with and without polycystic ovary syndrome. Hum Reprod. 2021 Nov 11:deab239. doi: 10.1093/humrep/deab239. Epub ahead of print. PMID: 34788426.
https://pubmed.ncbi.nlm.nih.gov/34788426/

Groombridge CJ, Maini A, Johnny C, McCreary D, Kim Y, Smit V, Fitzgerald M. Randomised controlled trial in cadavers investigating methods for intubation via a supraglottic airway device: Comparison of flexible airway scope guided versus a retrograde technique. Emerg Med Australas. 2021 Nov 27. doi: 10.1111/1742-6723.13908. Epub ahead of print. PMID: 34837890.
https://pubmed.ncbi.nlm.nih.gov/34837890/

Wong J, Lee JC, Grodski S, Yeung M, Serpell J. Cancer in thyroglossal duct cysts. ANZ J Surg. 2021 Nov 18. doi: 10.1111/ans.17369. Epub ahead of print. PMID: 34791748.
https://pubmed.ncbi.nlm.nih.gov/34791748/

Woodford K, Panettieri V, Ruben JD, Davis S, Tran Le T, Miller S, Senthi S. Oesophageal IGRT considerations for SBRT of LA-NSCLC: barium-enhanced CBCT and interfraction motion. Radiat Oncol. 2021 Nov 14;16(1):218. doi: 10.1186/s13014-021-01946-8. PMID: 34775990; PMCID: PMC8591953.
https://pubmed.ncbi.nlm.nih.gov/34775990/

Writing Committee for the REMAP-CAP Investigators, ..., Fitzgerald M, ..., Shankar-Hari M. Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial. JAMA. 2021 Nov 2;326(17):1690-1702. doi: 10.1001/jama.2021.18178. PMID: 34606578; PMCID: PMC8491132.
https://pubmed.ncbi.nlm.nih.gov/34606578/

Zhang J, Libianto R, Lee JC, Grodski S, Shen J, Fuller PJ, Yang J. Preoperative mineralocorticoid receptor antagonist reduces postoperative hyperkalaemia in patients with Conn syndrome. Clin Endocrinol (Oxf). 2021 Nov 6. doi: 10.1111/cen.14630. Epub ahead of print. PMID: 34743353.
https://pubmed.ncbi.nlm.nih.gov/34743353/