|Monitoring pressure of cerebral blood vessels in children with|
TBI may improve outcomes. Image: stmaryskids.org
The team investigated the pressure reactivity (PR) of cerebral blood vessels in these patients using a technique developed at Cambridge. Disturbance of PR is common after TBI in adults and is predictive of poor outcome, but has not been well studied in children. They found that loss of pressure reactivity was significantly associated with worse outcome, and that continuous monitoring of PR could enable an individualised approach to blood pressure targeting.
Reference: Lewis PM, Czosnyka M, Carter BG, Rosenfeld JV, Paul E, Singhal N, Butt W. Cerebrovascular pressure reactivity in children With traumatic brain injury. Pediatric Critical Care Medicine. 16(8):739-749, October 2015