CCS recent publications 11-31 October 2019

Prof Paul Myles is a co-author on a Lancet study
looking at anaesthetic depth and complications
after major surgery

Recent publications from Central Clinical School affiliated researchers in the following departments:

• Anaesthesia
• ACBD
• AIRmed
• Diabetes
• Infectious Diseases
• Melbourne Sexual Health Centre
• Neuroscience
• Peninsula Clinical School
• Surgery

Department of Anaesthesia and Perioperative Medicine

Short TG, Campbell D, Frampton C, Chan MTV, Myles PS, Corcoran TB, Sessler DI, Mills GH, Cata JP, Painter T, Byrne K, Han R, Chu MHM, McAllister DJ, Leslie K; Australian and New Zealand College of Anaesthetists Clinical Trials Network; Balanced Anaesthesia Study Group. Anaesthetic depth and complications after major surgery: an international, randomised controlled trial. Lancet. 2019 Oct 18. pii: S0140-6736(19)32315-3. doi: 10.1016/S0140-6736(19)32315-3. PMID: 31645286


Australian Centre for Blood Diseases

Lim HY, Brook R, Krishnamoorthi B, Tacey M, Leung T, Donnan G, Nandurkar H, Ho P. Global coagulation assays in patients with multiple myeloma and monoclonal gammopathy of unknown significance. Thromb Res. 2019 Oct 20;183:45-48. doi: 10.1016/j.thromres.2019.10.017.

Rana A, Westein E, Niego B, Hagemeyer CE. Shear-Dependent Platelet Aggregation: Mechanisms and Therapeutic Opportunities. Front Cardiovasc Med. 2019 Sep 20;6:141. doi: 10.3389/fcvm.2019.00141. eCollection 2019.


Department of Respiratory Allergy and Clinical Immunology (RACI)

Bousquet J, Schünemann HJ, Togias A, ...O'Hehir R, ... Allergic Rhinitis and Its Impact on Asthma Working Group. Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence. J Allergy Clin Immunol. 2019 Oct 15. pii: S0091-6749(19)31187-X. doi: 10.1016/j.jaci.2019.06.049.

Stevenson B1, Trevenen M2, Klinken E1, Smith W3, ..., Barnes S7, Spriggs K8, ... Lucas M14.  Multicenter Australian Study to Determine Criteria for Low- and High-Risk Penicillin Testing in Outpatients. J Allergy Clin Immunol Pract. 2019 Oct 8. pii: S2213-2198(19)30851-7. doi: 10.1016/j.jaip.2019.09.025.

Whitford H, Kure CE, Henriksen A, Hobson J, Snell GI3, Levvey BJ3, Marasco SF2, Gooi JH2, Zimmet A2, Negri J, Pick A, Buckland M, Williams T, Westall G, Paraskeva MA, Martin C, McGiffin DC. A donor PaO2/FiO2 < 300 mm Hg does not determine graft function or survival after lung transplantation. J Heart Lung Transplant. 2019 Sep 2. pii: S1053-2498(19)31666-3. doi: 10.1016/j.healun.2019.08.021. https://www.ncbi.nlm.nih.gov/pubmed/31636045


Department of Diabetes

Snelson M, Coughlan M. The Devil's in the Detail: The Importance of Specific, Descriptive Language for Reproducibility in Nutrition Science. J Ren Nutr. 2019 Oct 6. pii: S1051-2276(19)30272-9. doi: 10.1053/j.jrn.2019.07.002.

Tate M, Higgins GC, De Blasio MJ1, Lindblom R, ..., Coughlan MT, Ritchie RH . The Mitochondria-Targeted Methylglyoxal Sequestering Compound, MitoGamide, Is Cardioprotective in the Diabetic Heart. Cardiovasc Drugs Ther. 2019 Oct 25. doi: 10.1007/s10557-019-06914-9.

Wojtala M, Dąbek A, Rybaczek D, ..., El-Osta A, Balcerczyk A. Silencing Lysine-Specific Histone Demethylase 1 (LSD1) Causes Increased HP1-Positive Chromatin, Stimulation of DNA Repair Processes, and Dysregulation of Proliferation by Chk1 Phosphorylation in Human Endothelial Cells. Cells. 2019 Oct 7;8(10). pii: E1212. doi: 10.3390/cells8101212.


Department of Infectious Diseases

Carr A, Grund B, Schwartz AV, ..., Hoy JF; International Network for Strategic Initiatives in Global HIV Trials START bone mineral density substudy group. The rate of bone loss slows after 1-2 years of initial antiretroviral therapy: final results of the Strategic Timing of Antiretroviral Therapy(START) bone mineral density substudy. HIV Med. 2019 Oct 23. doi: 10.1111/hiv.12796.

Hall V, Wong M, Munsif M, ..., Cheng AC2,13, Stewardson AJ,..., Trubiano JA. Antimicrobial anaphylaxis: the changing face of severe antimicrobial allergy. J Antimicrob Chemother. 2019 Oct 21. pii: dkz422. doi: 10.1093/jac/dkz422.


Melbourne Sexual Health Centre

Blackshaw LCD, Chow EPF, Varma R, Healey L, Templeton DJ, Basu A, Turner D, Medland NA, Rix S, Fairley CK, Chen MY. Characteristics of recently arrived Asian men who have sex with men diagnosed with HIV through sexual health services in Melbourne and Sydney. Aust N Z J Public Health. 2019 Oct;43(5):424-428. doi: 10.1111/1753-6405.12926. Epub 2019 Jul 9. PMID 31287941

Durukan D, Read TRH, Murray G, Doyle M, Chow EPF, Vodstrcil LA, Fairley CK, Aguirre I, Mokany E, Tan LY, Chen MY, Bradshaw CS. Resistance-guided antimicrobial therapy using doxycycline-moxifloxacin and doxycycline-2.5g azithromycin for the treatment of Mycoplasma genitalium infection: efficacy and tolerability. Clin Infect Dis. 2019 Oct 20. pii: ciz1031. doi: 10.1093/cid/ciz1031. PMID: 31629365

Maddaford K, Fairley CK, Trumpour S, Chung M, Chow EPF. Sites in the oropharynx reached by different methods of using mouthwash: clinical implication for oropharyngeal gonorrhoea prevention.
Sex Transm Infect. 2019 Oct 18. pii: sextrans-2019-054158. doi: 10.1136/sextrans-2019-054158.
PMID: 31628249

Blackshaw LCD, Chow EPF, Varma R, Healey L, Templeton DJ, Basu A, Turner D, Medland NA, Rix S, Fairley CK, Chen MY. Characteristics of recently arrived Asian men who have sex with men diagnosed with HIV through sexual health services in Melbourne and Sydney. Aust N Z J Public Health. 2019 Oct;43(5):424-428. doi: 10.1111/1753-6405.12926. Epub 2019 Jul 9. PMID: 31287941


Department of Neuroscience

Ellis CA, Berkovic SF, Epstein MP, Ottman R; Epi4K Consortium.[inc. O'Brien TE], Bassel Abou-Khalil. The "maternal effect" on epilepsy risk: analysis of familial epilepsies and reassessment of prior evidence. Ann Neurol. 2019 Oct 21. doi: 10.1002/ana.25625. PMID: 31637767

Munji RN, Soung AL, Weiner GA, Sohet F, Semple BD, ..., Daneman R. Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module. Nat Neurosci. 2019 Oct 14. doi: 10.1038/s41593-019-0497-x. PMID:31611708

Tur C, Kalincik T, Oh J, Sormani MP, Tintoré M, Butzkueven H, Montalban X. Head-to-head drug comparisons in multiple sclerosis: Urgent action needed. Neurology. 2019 Oct 7. pii: 10.1212/WNL.0000000000008319. doi: 10.1212/WNL.0000000000008319.

van der Walt A. Addressing the treatment gap in MS-associated tremor: A new door opens. Mult Scler. 2019 Oct 16:1352458519880453. doi: 10.1177/1352458519880453. PMID: 31617440

Wright DK, Brady RD, Kamnaksh A, Trezise J, Sun M, McDonald SJ, Mychasiuk R, Kolbe SC, Law M, Johnston LA, O'Brien TJ, Agoston DV, Shultz SR. Repeated mild traumatic brain injuries induce persistent changes in plasma protein and magnetic resonance imaging biomarkers in the rat. Sci Rep. 2019 Oct 10;9(1):14626. doi: 10.1038/s41598-019-51267-w.PMID: 31602002


Peninsula Clinical School

Ayton D, Moran C, Berkovic D, Bateman C, Anderson K, Blair A, Soh SE, Morello R, Lim YY, Liew D. The Volunteer Dementia and Delirium Care (VDDC)©: A pre-implementation study exploring perceived acceptability to implementing the program in an acute and subacute metropolitan hospital. Australas J Ageing. 2019 Oct 15. doi: 10.1111/ajag.12725. PMID: 31617306

Ellis LJ, Bhullar H, Hughes K, Hunter-Smith DJ, Rozen WM. How should we manage women with fat necrosis following autologous breast reconstruction: An algorithmic approach. Breast J. 2019 Oct 11. doi: 10.1111/tbj.13661. PMID: 31602711


Department of Surgery

Bhullar HK, Aung AK, Graudins L, Ihle J, Gin D, Cleland H, Mei Teh B. Upper airway involvement in Stevens-Johnson syndrome and toxic epidermal necrolysis. Burns. 2019 Oct 4. pii: S0305-4179(18)30789-7. doi: 10.1016/j.burns.2019.09.006.

Cameron PA, Fitzgerald MC, ..., Matthew J, ..., Zalstein S; Australian Trauma Quality Improvement Program (AusTQIP) collaboration. Overview of major traumatic injury in Australia--Implications for trauma system design. Injury. 2019 Oct 3. pii: S0020-1383(19)30561-3. doi: 10.1016/j.injury.2019.09.036.

Lam TBL, MacLennan S, Willemse PM, ... Grummet JP, ... Mottet N.  EAU-EANM-ESTRO-ESUR-SIOG Prostate Cancer Guideline Panel Consensus Statements for Deferred Treatment with Curative Intent for Localised Prostate Cancer from an International Collaborative Study (DETECTIVE Study). Eur Urol. 2019 Oct 3. pii: S0302-2838(19)30740-7. doi: 10.1016/j.eururo.2019.09.020.