Congratulations to Dr Charbel Darido on his move to the VCCC!

Dr Charbel Darido receiving the highly sought after "No-Bell"
prize in 2013 for his outstanding avoidance of technical terms

After 5 years at Monash and almost 9 years in Stephen Jane’s lab, it has come to the day for me to bid adieu to you. If given a second chance, I'd still come to the same lab where I met geniuses and genuine colleagues along my journey. 

It would be remiss not to recall a little of my history and give credit to people from the Jane lab (since the Bone Marrow Research Laboratories at RMH), the Curtis lab and the Australian Centre for Blood Diseases who contributed towards progressing our projects and were the best colleagues in every aspect. I will be forever grateful to you.

Recent CCS publications: Week ending 15 April 2016

Figure 2 from the Darido publication: A schematic representation
of the cross-talk among key barrier genes, signaling transducers
and inflammatory factors

Recent publications with Central Clinical School affiliated authors:

Darido C, Georgy SR and Jane SM. The role of barrier genes in epidermal malignancy. Oncogene advance online publication 4 April 2016; 
Reference doi: 10.1038/onc.2016.84

de Valle E, Grigoriadis G, O'Reilly LA, Willis SN, Maxwell MJ, Corcoran LM, Tsantikos E, Cornish JK, Fairfax KA, Vasanthakumar A, Febbraio MA, Hibbs ML, Pellegrini M, Banerjee A, Hodgkin PD, Kallies A, Mackay F, Strasser A, Gerondakis S, Gugasyan R. NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells. J Exp Med. 2016 Apr; 213:621-41. 
Reference doi: 10.1084/jem.20151182.

Philpott AL, Fitzgerald PB, Bailey NW, Churchyard A, Georgiou-Karistianis N, Cummins TD. A GABBR2 gene variant modifies pathophysiology in Huntington's disease. Neurosci Lett. 2016 Mar; 620:8-13.
Reference doi: 10.1016/j.neulet.2016.03.038.

Prichard R, Rossi M, Muir J, Yao C, Whelan K, Lomer M. Fermentable oligosaccharide, disaccharide, monosaccharide and polyol content of foods commonly consumed by ethnic minority groups in the United Kingdom. Int J Food Sci Nutr. 2016 Mar:1-8 (online).  
Reference doi: 10.3109/09637486.2016.1163328

CCS successes in 2015 NHMRC funding

Monash research on head and neck cancer provides first real breakthrough in decades

The research group which published this paper. L-R: Dr Charbel
Darido, Ms Seema Srivastava, Mr Michael Cangkrama, Prof
Stephen Jane, Dr Smitha Georgy, Dr Seb Dworkin, Ms Alana
Auden. Not present: Dr Darren Partridge, Prof Catriona McLean

Research published this week in the prestigious Journal of the National Cancer Institute provides the first real insight in more than 50 years as to how head and neck cancers – one of the more deadly forms of cancer – develop. The discovery opens the way to identifying patients with particular types of head and neck cancer that may be candidates for more targeted therapies.

Michael Cangkrama: What underlies skin diseases?

Michael Cangkrama's research looks at skin development and diseases. His particular topic is "Analysis of the grainyhead-like genes in mammalian development and disease".  Michael is a PhD student in the Department of Medicine, in the Epidermal Development Laboratory and his supervisors are Professor Stephen Jane and Dr Charbel Darido.  To read more, visit: http://www.med.monash.edu.au/cecs/education/profiles/cangkrama.html