29 May 2014

Mechanisms of retinopathy in premature babies teased out: Immunology research

ARS cover image is by
Dr Devy Deliyanti, one
of the paper's authors
Effective preventive therapies for retinopathy of prematurity (ROP) don't exist, yet globally, there are at least 50,000 children blind from ROP. Professor Jennifer Wilkinson-Berka in the Department of Immunology leads research efforts into understanding the problem. A recently published paper shows that one form of a particular enzyme complex called NADPH oxidase (NOX) is involved in the development of retinopathy. The research indicates that blocking the action of NOX1 prevents the damage from occurring. Reference: NADPH Oxidase, NOX1, Mediates Vascular Injury in Ischemic Retinopathy. Antioxidants & Redox Signaling. V 20, No 17, 2014 DOI: 10.1089/ars.2013.5357

Multiple sclerosis research by Dr Steven Petratos receives funding

Dr Steven Petratos des-
cribes his research
Congratulations to Dr Steven Petratos, who has been successful in obtaining a highly competitive grant to further his research on multiple sclerosis (MS). The award was made by the US based National MS Society. It is a pilot grant for USD40,000, and the topic is "Delineating the role of the monocarboxylate transporter 8 (MCT8) in driving oligodendrocyte precursor cell maturation". MCT8 carries thyroid hormone, and when it doesn't work there's a problem with myelination, as with MS.
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