Video of the week: Prof Fabienne Mackay on lupus control through B cell tweaking

"Lupus Fabienne Mackay" - These search terms will pull up our new video where Professor Fabienne Mackay explains her group's recent discovery on how to stop lupus without stopping the immune system by focussing on a specific receptor (called TACI) found on B cells - the 'soldiers' of the immune system.

Video link: https://www.youtube.com/watch?v=W1EmIuuhu9U

Forthcoming CCS events: Seminars, public events, general notices

Paddy Dempsey at the 2014
CCS postgraduate symposium

Central Clinical School has regular seminar series and postgraduate presentations. All event notices are maintained on the CCS Events calendar.

CCS staff & students can see details of both public and local events (including professional development courses, trade fairs and Graduate Research Student calendars) and deadlines, at the Intranet's Announcements page.

Various Departments have their own calendars, see CCS seminar index: www.med.monash.edu.au/cecs/events/seminars.html

What's on for this week: 3 - 7 Aug 2015

Mon Aug 3 12:30 ► Psychiatry Professorial Grand Round Tue Aug 4 1:00 PM ► CCS 3MT thesis heat Tue Aug 4 3:30 PM ► PhD Mid-candidature review - Mr Paddy Dempsey 4:00 PM ► PhD Pre-submission review seminar - Mr Anmar Khan Fri Aug 7 12:30 PM ► PhD Pre-submission review - Ms Janine Trevillyan 17:00 ► Deadline: Early Career Fellowship in Asthma Research

In the Future

• 13 Aug CCS student information night
• 30 Aug De Castella Run
• 30 Sep Translational Research symposium: Alfred Medicine 50th anniversary
• 9 Oct CCS Public Lecture: Prof Jayashri Kulkarni on women's mental health

Professor Jayashri Kulkarni: Psychiatry in the 21st century. Find out more on 30 Sep 2015

Professor Jayashri Kulkarni is a Professor of Psychiatry and the director of Monash Alfred Psychiatry Research Centre (MAPrc) – one Australia’s largest and most innovative centres for clinical mental health research. She is internationally recognised for her expertise in the treatment of mental illness, particularly in women’s mental health. She has pioneered the use of estrogen as a treatment in schizophrenia and has developed many other innovative treatments for mental illnesses. Jayashri will be speaking at the forthcoming 30 Sept Translational Research symposium hosted by Central Clinical School. See detail below.

4 Aug 2015 3MT CCS heat is on: See our students compete! All welcome

The Central Clinical School is holding its 3MT thesis heat to select a finalist to compete in the Faculty heat, on Tuesday 4 August 2015. Please come along and support our participants. See more detail & RSVP for catering (lunch is provided courtesy Monash Postgraduate Association sponsorship) at:
www.med.monash.edu.au/cecs/education/hdr-3mt.html

 Ashlee Conway (ACBD)
Topic: The characterisation of red cell mutants identified in an ENU mutagenesis screen

Dominik Draxler (ACBD)
Topic: The plasminogen activation system in traumatic brain injury

Paddy Dempsey (Baker IDI)
Topic: Breaking up prolonged sitting - implications for prevention and management of Type 2 diabetes

Andrew Guy (Immunology/Burnet)
Topic: Assessing disordered proteins in Plasmodium falciparum and their importance as targets of protective humoral immunigy against symptomatic malaria

Shanzana Khan (Baker IDI)
Topic: The influence of Y Chromosome Lineage in determining vascular function, inflammation and blood pressure regulation



Waled Shihata (Baker IDI)
Topic: Pathophysiological effects of high intraluminal pressure on cardiovascular disease

See more & RSVP at www.med.monash.edu.au/cecs/education/hdr-3mt.html

Medical student creativity shines in AXM logo competition

L-R: AXM creator A/Prof Rob Selzer, Mr Lewis Ronan (the
winner with his winning design) and Ms Fiona Foley, AXM
project coordinator.

AXM, the innovative learning tool for medical students developed by Monash University is now the proud owner of its very own logo! (see below)
A competition was held for medical students to get creative and design a logo for AXM. AXM was launched in mid-2014 and is currently being used by over 200 third year medical students across Victoria. A total of 49 entries from 16 medical students were submitted and presented a very tough job for the judging panel!

Journal of Autoimmunity selects Immunology paper for highlight

Congratulations to the Department of Immunology authors for the selection of their paper “BAFF-driven autoimmunity requires CD19 expression” for being made free access and highlighted on the homepage Journal of Autoimmunity for six months.Journal of Autoimmunity.

Publication: The unique symptom profile of perimenopausal depression

Perimenopause is associated with increased depression symptoms in women. Symptoms at this time are thought to be qualitatively different from those in childbearing years. This research investigated whether depressive symptoms during perimenopause can be distinguished from those in the childbearing years.

Publication: What modulates the oxidative stress response in pathogenic microorganisms?

Sirtuins are an ancient family of NAD+-dependent deacylases connected with the regulation of fundamental cellular processes including metabolic homeostasis and genome integrity. We show the existence of a hitherto unrecognized class of sirtuins, found predominantly in microbial pathogens. In contrast to earlier described classes, these sirtuins exhibit robust protein ADP-ribosylation activity.