12 Jun 2019
Clot-busting drug may affect stroke patients’ immune system: study
by Anne Crawford
A study by Monash University’s Australian Centre for Blood Diseases (ACBD) into a drug commonly used to remove blot clots in stroke suggests it may weaken the immune system.
The study, published in Frontiers in Immunology, found that t-PA (tissue-type
plasminogen activator) affected several aspects related to the immune system in a mouse model of acute ischemic stroke (AIS). Ischemic stroke is caused when a blood vessel supplying blood to the brain is obstructed by a clot, and accounts for 80 per cent of all types of stroke. It is a leading cause of disability and mortality worldwide.
A study by Monash University’s Australian Centre for Blood Diseases (ACBD) into a drug commonly used to remove blot clots in stroke suggests it may weaken the immune system.
The study, published in Frontiers in Immunology, found that t-PA (tissue-type
plasminogen activator) affected several aspects related to the immune system in a mouse model of acute ischemic stroke (AIS). Ischemic stroke is caused when a blood vessel supplying blood to the brain is obstructed by a clot, and accounts for 80 per cent of all types of stroke. It is a leading cause of disability and mortality worldwide.
3MT Comp Winners!
| CCS Competition winner Lakshanie Wickramasinghe |
CCS Recent Publications: 27th May - 10th June 2019
Recent publications for Central Clinical School feature affiliated authors in the following departments:
- MAPrc
- ACBD
- Anaesthesia & Perioperative Medicine
- Neuroscience
- Diabetes
- Melbourne Sexual Health Centre
- Immunology & Pathology
- Gastroenterology
- Surgery
5 Jun 2019
Translational Research Symposium Speaker Spotlight: Professor Gail Risbridger
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| Professor Gail Risbridger |
The Plenary speaker for the event is Professor Gail Risbridger, Deputy Dean, Special Projects, Monash Partners Comprehensive Cancer Consortium and Research Director, Prostate Cancer Research Program.
29 May 2019
Spotlight on MS Research
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| Dr Steven Petratos and Dr Erica Kim |
When Dr Erica Kim began her honours degree in the Neuroscience Department at Central Clinical School, she arrived with simply a passion for neuroscience. Now, with a PhD completed, along with two first author primary research papers, 2 author reviews and contributing author credits, it seems that this researcher is in it for the long haul with a firm focus on developing cell and gene-based therapies to treat intractable neurodegenerative disease, particularly Multiple Sclerosis.
Investigative research is a slow burn, particularly at a molecular level. It can take years to see a project translate from the investigative to pre-clinical stages and then there is no guarantee of progression to a clinical trial. Erica is keen to witness her earlier research progress into clinical trials. The molecules that have been the focus of her work, which may contribute or initiate such damage in MS are becoming known and by targeting them, it may be possible to limit the destruction, which occurs to nerve fibres in the brain and spinal cord, promoting a better clinical outcome for individuals living with MS.
Public Health researcher wins Prestigious Alumni Award
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| A/Prof. Chow receives his award from Professor Rodney Phillips, Dean of the Faculty of Medicine, UNSW |
categories spanning science and technology to arts and services to the community.
Eric made a career change in 2012 by completing a Master of Public Health followed by a PhD at UNSW Sydney, where he received the Faculty of Medicine Dean’s List. The MPH provided Eric with new knowledge in public health, epidemiology, biostatistics, health promotion and mathematical modelling. His PhD thesis, which focused on HIV epidemiology and sexual practice among at-risk populations in China, has paved the way for his impressive research in the field of sexual health.
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