Plasma cell survival research

Research on plasma cell survival by Associate Professor Mark Wright (Dept of Immunology) and colleagues, published in Science Signalling, was highlighted in a recent Nature Immunology research review. Mark’s research is on the role of an protein called CD37 in the tetraspanin family of proteins. CD37 is formed on the surface of B cells and together with many other tetraspanins, it organises traffic through the cell membrane.
The CD37 protein interacts with, and organises various other important proteins to behave as required for the cell’s health, survival and productivity. See review article, http://www.nature.com/ni/journal/v14/n1/full/ni.2505.html. See original article: http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/250/ra82?view=abstract