Investigating Alzheimer's disease

PhD student Judy Allen-Graham completed her thesis in 2012, titled ‘Inhibition of APP and APLP2 using siRNA to investigate protein function and Alzheimer's disease’, on functional redundancy between the Alzheimer’s protein APP and its homologue APLP2. APP, the amyloid precursor protein of Alzheimer’s disease, and its homologue APLP2 are found in a segmental distribution on the surface of neurites in cortical neurons in primary culture.
Judy's thesis was passed in April 2013. Her supervisors were Dr Louise Kelly and Professor Elsdon Storey, Head of the Van Cleef/Roet Centre for Nervous Diseases.