3-9 Nov 2020 Central Clinical School publications

Non-alcoholic fatty liver disease burden grows as people become
fatter: Study. Image: Shutterstock

Recent publications featuring research as notified by PubMed during 3-9 November 2020 from Central Clinical School affiliated researchers in the following departments. The below is not a comprehensive list:

• Australian Centre for Blood Diseases
• Diabetes
• Gastroenterology
• Immunology and Pathology
• Infectious Diseases
• Medicine - Alfred & Peninsula
• Melbourne Sexual Health Centre
• Neuroscience
• Surgery

Department of Anaesthesiology and Perioperative Medicine

El-Boghdadly K, Wong DJN, Owen R, ..., Myles PS, ..., Ahmad I. Risks to healthcare workers following tracheal intubation of patients with COVID-19: a prospective international multicentre cohort study. Anaesthesia. 2020 Nov;75(11):1437-1447. doi: 10.1111/anae.15170. Epub 2020 Jul 9. PMID: 32516833; PMCID: PMC7300828.


Australian Centre for Blood Diseases

Reale A, Khong T, Mithraprabhu S, Savvidou I, Hocking J, Bergin K, Ramachandran M, Chen M, Dammacco F, Ria R, Silvestris F, Vacca A, Reynolds J, Spencer A. TOP2A expression predicts responsiveness to carfilzomib in myeloma and informs novel combinatorial strategies for enhanced proteasome inhibitor cell killing. Leuk Lymphoma. 2020 Oct 31:1-11. doi: 10.1080/10428194.2020.1832659. Epub ahead of print. PMID: 33131357.


Department of Diabetes

Pitsillou E, Liang J, Karagiannis C, Ververis K, Darmawan KK, Ng K, Hung A, Karagiannis TC. Interaction of small molecules with the SARS-CoV-2 main protease in silico and in vitro validation of potential lead compounds using an enzyme-linked immunosorbent assay. Comput Biol Chem. 2020 Oct 23;89:107408. doi: 10.1016/j.compbiolchem.2020.107408. Epub ahead of print. PMID: 33137690; PMCID: PMC7583591.


Department of Gastroenterology

Adams LA, Roberts SK, Strasser SI, Mahady SE, Powell E, Estes C, Razavi H, George J. Nonalcoholic fatty liver disease burden: Australia, 2019-2030. J Gastroenterol Hepatol. 2020 Sep;35(9):1628-1635. doi: 10.1111/jgh.15009. Epub 2020 Feb 26. PMID: 32048317; PMCID: PMC7540570.


Department of Immunology and Pathology

van Langelaar J, Wierenga-Wolf AF, Samijn JPA, ..., van Zelm MC, Smolders J, van Luijn MM. The association of Epstein-Barr virus infection with CXCR3+ B-cell development in multiple sclerosis impact of immunotherapies. Eur J Immunol. 2020 Nov 5. doi: 10.1002/eji.202048739. Epub ahead of print. PMID: 33152118.


Department of Infectious Diseases

See James McMahon's video explaining the trial

McMahon JH, Lau JSY, Roney J, Rogers BA, Trubiano J, Sasadeusz J, Molton JS, Gardiner B, Lee SJ, Hoy JF, Cheng A, Peleg AY. An adaptive randomised placebo controlled phase II trial of antivirals for COVID-19 infection (VIRCO): A structured summary of a study protocol for a randomised controlled trial. Trials. 2020 Oct 13;21(1):847. doi: 10.1186/s13063-020-04766-5. PMID: 33050947; PMCID: PMC7552590.

Saag MS, Gandhi RT, Hoy JF, ..., Volberding PA. Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2020 Recommendations of the International Antiviral Society-USA Panel. JAMA. 2020 Oct 27;324(16):1651-1669. doi: 10.1001/jama.2020.17025. PMID: 33052386.


Department of Medicine - Peninsula

Bernhardt J, Borschmann K, Collier JM, ..., Srikanth V, Read SJ, Donnan GA; AVERT Trialists Collaboration Group. Fatal and non-fatal events within 14 days after early, intensive mobilization post stroke. Neurology. 2020 Nov 3:10.1212/WNL.0000000000011106. doi: 10.1212/WNL.0000000000011106. Epub ahead of print. PMID: 33144512.

McTaggart RA, Holodinsky JK, Ospel JM, ..., Phan TG, Beare R, ..., Jayaraman MV. Leaving No Large Vessel Occlusion Stroke Behind: Reorganizing Stroke Systems of Care to Improve Timely Access to Endovascular Therapy. Stroke. 2020 Jul;51(7):1951-1960. doi: 10.1161/STROKEAHA.119.026735. Epub 2020 Jun 17. PMID: 32568640.

O'Donnell R, Savaglio M, Skouteris H, Banaszak-Holl J, Moran C, Morris H, Vicary D, Ayton D. The Effectiveness of Transition Interventions to Support Older Patients From Hospital to Home: A Systematic Scoping Review. J Appl Gerontol. 2020 Nov 6:733464820968712. doi: 10.1177/0733464820968712. Epub ahead of print. PMID: 33155499.

Zhang W, Anderson CS, Kilkenny MF, Kim J, Dewey HM, Andrew NE, Lannin NA, Thrift AG, Grimley R, Sundararajan V, Cadilhac DA. Hospital admissions prior to primary intracerebral haemorrhage and relevant factors associated with survival. J Stroke Cerebrovasc Dis. 2020 Sep;29(9):105026. doi: 10.1016/j.jstrokecerebrovasdis.2020.105026. Epub 2020 Jun 24. PMID: 32807441.


Department of Neuroscience

Jones F, Gombert- K, Honey S, Cloud G, Harris R, Macdonald A, McKevitt C, Robert G, Clarke D. Addressing inactivity after stroke: The Collaborative Rehabilitation in Acute Stroke (CREATE) study. Int J Stroke. 2020 Nov 2:1747493020969367. doi: 10.1177/1747493020969367. Epub ahead of print. PMID: 33138735.

Vajda FJE, O'Brien TJ, Graham JE, Hitchcock AA, Perucca P, Lander CM, Eadie MJ. Twin pregnancy in women with epilepsy. Epilepsia. 2020 Nov 2. doi: 10.1111/epi.16727. Epub ahead of print. PMID: 33140408.


Department of Surgery

Burton PR. Outcomes of single versus two stage oesophagectomy for squamous cell carcinoma. EClinicalMedicine. 2020 Oct 24;28:100606. doi: 10.1016/j.eclinm.2020.100606. PMID: 33134906; PMCID: PMC7588692.

Langmaid T, Jassal K, Meher-Homji Z, Lee JC, Serpell J, Yeung M, McMahon J, Grodski S. Disseminated nocardiosis with adrenal abscess masquerading as metastatic adrenal cancer in an immunocompetent adult. ANZ J Surg. 2020 Nov 2. doi: 10.1111/ans.16423. Epub ahead of print. PMID: 33137243.

McInnes E, Dale S, Craig L, ..., Fitzgerald M, ..., Middleton S. Process evaluation of an implementation trial to improve the triage, treatment and transfer of stroke patients in emergency departments (T3 trial): a qualitative study. Implement Sci. 2020 Nov 4;15(1):99. doi: 10.1186/s13012-020-01057-0. PMID: 33148343; PMCID: PMC7640433.