Closing in on an optimal molecule for kidney injury

A designer molecule goes exactly where
it is needed for protection against kidney
injury during transplantation.

by Anne Crawford

Kidney ischemia-reperfusion injury (IRI) is common during transplantation, leading to compromised function in the kidney and increasing the chance of rejection of the new organ.

Now scientists in the Vascular Biology Group, Australian Centre for Blood Diseases, have refined a designer molecule that offers protection against IRI in research that may have translational significance to transplantation.

Jay Jha is CCS's 20th PhD completion for 2014! Congratulations Jay!

Mr Jay Jha has been awarded the degree of Doctor of Philosophy. Jay did his research at the Baker IDI Heart and Diabetes Institute. His research is on the complications of diabetes, especially in relation to kidney disease. Jay's supervisor is Professor Karin Jandeleit-Dahm.

Jay’s thesis is titled "Role of NADPH oxidases NOX1 and NOX4 in diabetic nephropathy: Genetic Deletion and Pharmacological inhibition studies" and was accepted in fulfilment of the requirements for the degree by the Graduate Research Steering Committee on Tuesday 2 December 2014.

See more about Jay on his Student Profile.

Jay Jha: PhD research investigates diabetes and kidney disease

Jay is a PhD student at the Baker IDI Heart and Diabetes Institute and his research is based on the complications of diabetes, especially in relation to kidney disease. Jay's supervisor is Professor Karin Jandeleit-Dahm. To read more about Jay go to: www.med.monash.edu.au/cecs/education/profiles/jha.html