New diabetic kidney disease target raises hopes

Professor Karin Jandeleit-Dahm and Dr Jay Chandra Jha

by Anne Crawford

Monash University scientists are developing what could be a promising new therapeutic target to combat diabetic kidney disease. 

The Central Clinical School researchers led by Professor Karin Jandeleit-Dahm and Dr Jay Chandra Jha, together with an international collaboration, recently revealed details of the predominantly pathological role of the pro-oxidant enzyme NOX5 in diabetic complications, particularly diabetic kidney disease (DKD), and are working on small molecule inhibitors to target it. 

CCS diabetes researcher honoured by award

Dr Jay Jha won an ADS award

Scientist Dr Jay Jha has been recognised by the Australian Diabetes Society (ADS) in an award given at its recent annual meeting in Sydney.

Dr Jha, an NHMRC Early Career Research Fellow in the Monash Department of Diabetes, won the Basic Science Poster award for his work into Nox4 and Nox5, pro-oxidant enzymes believed to promote diabetic kidney disease.