New proteins discovered in brain injury

Schematic of overall experimental design for the proteomics analysis.
CSF = cerebrospinal fluid; TBI = traumatic brain injury;
TMT = tandem mass tag labeling. Image: Fig. 1 in the study

A team from Monash University’s Department of Neuroscience in Melbourne, Australia, collaborating with the Monash Proteomics and Metabolomics Facility, has found new proteins affected by brain injury which may represent new biomarkers, or biological indicators, of injury. 

It remains a significant clinical challenge to accurately predict long-term outcomes for a patient who sustains a severe traumatic brain injury.