by Ms Kerrui Wong, Ms Marissa Sgro and Dr Loretta Piccenna
Adolescence is a sensitive period for bone development. Changes during this critical period may lead to significant long-term complications, for example osteopenia and osteoporosis later in life. New research from the Monash Trauma group in the Department of Neuroscience at the Central Clinical School indicates that weakening of the gut microbiome with antibiotic treatment and repetitive mild traumatic brain injury each individually stunted bone growth and volume, and did so in a sex-dependent manner during adolescence.
| Scans of the femur bone density and volume with different treatments using microcomputed tomography |