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| Ex vivo scans of hearts from fibrotic (left) and control mice which were administered a unique fluorescent peptide that targets collagen type I. A striking enhancement of the damaged heart ventricles is observed. Image: Figure 5 in study |
Cardiac fibrosis is a scarring process causing excess deposition of collagen in the heart, leading to distortion of its architecture and function. It is a significant disease feature in many cardiac conditions, including heart failure, atrial fibrillation (AF) and myocardial infarction (MI).
