16 Dec 2022

Congratulations to Merlin Thomas on NHMRC Development grant

Congratulations to Professor Merlin Thomas, Department of Diabetes, who has been awarded a National Health and Medical Research Council (NHMRC) Development grant. 

Prof Thomas has been awarded $998,513 over three years for his application, "Splice switching oligonucleotides for the treatment of chronic kidney disease".

Prof Thomas said, "RNA [which converts information stored in DNA into proteins] can now be used to safely and selectively treat human diseases.

"RNA can be used as a template to make a new protein, such as in mRNA vaccines.

"But RNA can also be used change how coding elements are spliced together and the protein that results from them.

"This strategy has recently been used to great effect in difficult-to-treat diseases, like muscular dystrophy. We will now apply this same disruptive RNA technology to develop a novel treatment for chronic kidney disease," he said.

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