PADDI Trial results webinar: 6 May, 7-8 am

The Australian and New Zealand College of Anaesthetists Clinical Trials Network (ANZCA CTN) and Monash University are delighted to invite you to a virtual public webinar announcing the results of the Perioperative Administration of Dexamethasone and Infection (PADDI) trial. The webinar will be held on Thursday 6 May, 2021 at 7-8am AEST. (Note, flyer with international times here). More information and register here.

Surprising finding following infection after paediatric brain injury

Mr Rishabh Sharma, first author on the study

Traumatic brain injury (TBI) is a major cause of disability in young children, yet the factors contributing to poor outcomes in this population are not well understood. What most people don’t know is that patients who experience a TBI are highly susceptible to infections originating in hospitals, and are mostly acquired within the first week of hospitalization. Such infections may modify the pathobiology and recovery of TBI.

Mr Rishabh Sharma is a 3rd year PhD student supervised by Dr Bridgette Semple, A/Prof. Sandy Shultz and Dr. Pablo Casillas-Espinosa in the Department of Neuroscience at the Central Clinical School. He wanted to understand whether an additional challenge to the immune system (i.e. mimicking an infection) after paediatric TBI altered the acute outcomes in a pre-clinical mouse model.